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Social context prevents heat hormetic effects against mutagens during fish development.

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Title: Social context prevents heat hormetic effects against mutagens during fish development.
Authors: Feugere, Lauric1 (AUTHOR), Silva De Freitas, Claudio1 (AUTHOR), Bates, Adam1 (AUTHOR), Storey, Kenneth B.2 (AUTHOR), Beltran‐Alvarez, Pedro3 (AUTHOR), Wollenberg Valero, Katharina C.1,4,5 (AUTHOR) katharina.wollenbergvalero@ucd.ie
Source: FEBS Letters. Aug2025, Vol. 599 Issue 15, p2107-2128. 22p.
Subjects: Social context, Physiological effects of temperature, Laboratory zebrafish, Ultraviolet radiation, Physiological adaptation, Transcriptomes, Mutagens
Abstract: Since stress can be transmitted to congeners via social metabolites, it is paramount to understand how the social context of abiotic stress influences aquatic organisms' responses to global changes. Here, we integrated the transcriptomic and phenotypic responses of zebrafish embryos to a UV damage/repair assay following scenarios of heat stress, its social context and their combination. Heat stress preceding UV exposure had a hormetic effect through the cellular stress response and DNA repair, rescuing and/or protecting embryos from UV damage. However, experiencing heat stress within a social context negated this molecular hormetic effect and lowered larval fitness. We discuss the molecular basis of interindividual chemical transmission within animal groups as another layer of complexity to organisms' responses to environmental stressors. [ABSTRACT FROM AUTHOR]
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Database: Engineering Source
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Abstract:Since stress can be transmitted to congeners via social metabolites, it is paramount to understand how the social context of abiotic stress influences aquatic organisms' responses to global changes. Here, we integrated the transcriptomic and phenotypic responses of zebrafish embryos to a UV damage/repair assay following scenarios of heat stress, its social context and their combination. Heat stress preceding UV exposure had a hormetic effect through the cellular stress response and DNA repair, rescuing and/or protecting embryos from UV damage. However, experiencing heat stress within a social context negated this molecular hormetic effect and lowered larval fitness. We discuss the molecular basis of interindividual chemical transmission within animal groups as another layer of complexity to organisms' responses to environmental stressors. [ABSTRACT FROM AUTHOR]
ISSN:00145793
DOI:10.1002/1873-3468.70047