Effect of Ionizing Radiation on the Electrostatic Properties of Gold Nanoparticles.

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Bibliographic Details
Title: Effect of Ionizing Radiation on the Electrostatic Properties of Gold Nanoparticles.
Authors: Azarkin, M. Yu.1 (AUTHOR) azarkinmy@lebedev.ru, Kirakosyan, M. R.1 (AUTHOR) kirakosyanmr@lebedev.ru
Source: JETP Letters. Nov2025, Vol. 122 Issue 9, p562-567. 6p.
Subjects: Ionizing radiation, Gold nanoparticles, Cytotoxins, Radiation therapy equipment, Surface charges, Monte Carlo method, Electrostatics
Abstract: In this study, the effect of γ-radiation from typical commercial medical sources based on X-ray tubes and linear accelerators on the electrostatic properties of radiosensitizing gold nanoparticles located in a tissue-like medium has been evaluated numerically using a Monte Carlo simulation in the Geant4 software package. It has been shown that for realistic radiation doses, a significant fraction of gold nanoparticles of up to ~10‒1 can, at least temporarily, change their surface charge sufficiently to convert anionic gold nanoparticles into cationic ones, which can lead to cytotoxic effects. [ABSTRACT FROM AUTHOR]
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Database: Engineering Source
Description
Abstract:In this study, the effect of γ-radiation from typical commercial medical sources based on X-ray tubes and linear accelerators on the electrostatic properties of radiosensitizing gold nanoparticles located in a tissue-like medium has been evaluated numerically using a Monte Carlo simulation in the Geant4 software package. It has been shown that for realistic radiation doses, a significant fraction of gold nanoparticles of up to ~10‒1 can, at least temporarily, change their surface charge sufficiently to convert anionic gold nanoparticles into cationic ones, which can lead to cytotoxic effects. [ABSTRACT FROM AUTHOR]
ISSN:00213640
DOI:10.1134/S0021364025608292