Effect of Ionizing Radiation on the Electrostatic Properties of Gold Nanoparticles.

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Title: Effect of Ionizing Radiation on the Electrostatic Properties of Gold Nanoparticles.
Authors: Azarkin, M. Yu.1 (AUTHOR) azarkinmy@lebedev.ru, Kirakosyan, M. R.1 (AUTHOR) kirakosyanmr@lebedev.ru
Source: JETP Letters. Nov2025, Vol. 122 Issue 9, p562-567. 6p.
Subjects: Ionizing radiation, Gold nanoparticles, Cytotoxins, Radiation therapy equipment, Surface charges, Monte Carlo method, Electrostatics
Abstract: In this study, the effect of γ-radiation from typical commercial medical sources based on X-ray tubes and linear accelerators on the electrostatic properties of radiosensitizing gold nanoparticles located in a tissue-like medium has been evaluated numerically using a Monte Carlo simulation in the Geant4 software package. It has been shown that for realistic radiation doses, a significant fraction of gold nanoparticles of up to ~10‒1 can, at least temporarily, change their surface charge sufficiently to convert anionic gold nanoparticles into cationic ones, which can lead to cytotoxic effects. [ABSTRACT FROM AUTHOR]
Copyright of JETP Letters is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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  Data: <searchLink fieldCode="DE" term="%22Ionizing+radiation%22">Ionizing radiation</searchLink><br /><searchLink fieldCode="DE" term="%22Gold+nanoparticles%22">Gold nanoparticles</searchLink><br /><searchLink fieldCode="DE" term="%22Cytotoxins%22">Cytotoxins</searchLink><br /><searchLink fieldCode="DE" term="%22Radiation+therapy+equipment%22">Radiation therapy equipment</searchLink><br /><searchLink fieldCode="DE" term="%22Surface+charges%22">Surface charges</searchLink><br /><searchLink fieldCode="DE" term="%22Monte+Carlo+method%22">Monte Carlo method</searchLink><br /><searchLink fieldCode="DE" term="%22Electrostatics%22">Electrostatics</searchLink>
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  Data: In this study, the effect of γ-radiation from typical commercial medical sources based on X-ray tubes and linear accelerators on the electrostatic properties of radiosensitizing gold nanoparticles located in a tissue-like medium has been evaluated numerically using a Monte Carlo simulation in the Geant4 software package. It has been shown that for realistic radiation doses, a significant fraction of gold nanoparticles of up to ~10‒1 can, at least temporarily, change their surface charge sufficiently to convert anionic gold nanoparticles into cationic ones, which can lead to cytotoxic effects. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of JETP Letters is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1134/S0021364025608292
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      – Code: eng
        Text: English
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        PageCount: 6
        StartPage: 562
    Subjects:
      – SubjectFull: Ionizing radiation
        Type: general
      – SubjectFull: Gold nanoparticles
        Type: general
      – SubjectFull: Cytotoxins
        Type: general
      – SubjectFull: Radiation therapy equipment
        Type: general
      – SubjectFull: Surface charges
        Type: general
      – SubjectFull: Monte Carlo method
        Type: general
      – SubjectFull: Electrostatics
        Type: general
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      – TitleFull: Effect of Ionizing Radiation on the Electrostatic Properties of Gold Nanoparticles.
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              M: 11
              Text: Nov2025
              Type: published
              Y: 2025
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