Synthesis, characterization and crystal structures of N′-(2-hydroxy-4-methoxybenzylidene)-3-methylbenzohydrazide and it's copper(II), cobalt(III) and zinc(II) complexes with antibacterial activity.
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| Title: | Synthesis, characterization and crystal structures of N′-(2-hydroxy-4-methoxybenzylidene)-3-methylbenzohydrazide and it's copper(II), cobalt(III) and zinc(II) complexes with antibacterial activity. |
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| Authors: | Mao, Fu-Lin1 (AUTHOR) xpzhougroup@163.com |
| Source: | Inorganica Chimica Acta. May2026, Vol. 594, pN.PAG-N.PAG. 1p. |
| Subjects: | Crystal structure, Metal complexes, Antibacterial agents, Hydrazone derivatives, Zinc, Materials testing, Copper, Chemical synthesis |
| Abstract: | An aroylhydrazone compound N′ -(2-hydroxy-4-methoxybenzylidene)-3-methylbenzohydrazide (H 2 L) was prepared and characterized by IR, UV–Vis, 1H and 13C NMR spectra. Reaction of H 2 L with copper nitrate, cobalt nitrate and zinc iodide, respectively, afforded three new complexes [Cu 2 (HL) 2 (ONO 2) 2 ]∙2H 2 O (1 ∙2H 2 O), [Co 2 L 2 (EtOH) 2 (OH 2) 2 ]2NO 3 (2), and [Zn 2 I 2 (HL) 2 ]∙2EtOH (3 ∙2EtOH). The complexes have been characterized by IR and UV–Vis spectra. Structures of H 2 L and the complexes were further confirmed by single crystal X-ray determination. H 2 L crystallizes in monoclinic system space group P 2 1 / c , and the three complexes in triclinic P -1. Single crystal X-ray diffraction analysis reveals that the Cu atoms in 1 and Zn atoms in 3 are in square pyramidal coordination, and the Co atoms in 2 are in octahedral coordination. The compounds were assayed against the bacterial strains Bacillus subtillis , Staphylococcus aureus , Escherichia coli , and Pseudomonas aereuguinosa. The Cu and Zn complexes have effective antibacterial activities. [Display omitted] • The aroylhydrazone compound N′ -(2-hydroxy-4-methoxybenzylidene)-3-methylbenzohydrazide was newly synthesized. • The three complexes were newly synthesized. • Single crystal structures of the aroylhydrazone compound and the complexes were first reported. • The complexes have potential antibacterial activities on the bacterial strains Bacillus subtillis , Staphylococcus aureus , Escherichia coli , and Pseudomonas aereuguinosa. [ABSTRACT FROM AUTHOR] |
| Copyright of Inorganica Chimica Acta is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 191350126 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Synthesis, characterization and crystal structures of N′-(2-hydroxy-4-methoxybenzylidene)-3-methylbenzohydrazide and it's copper(II), cobalt(III) and zinc(II) complexes with antibacterial activity. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Mao%2C+Fu-Lin%22">Mao, Fu-Lin</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> xpzhougroup@163.com</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Inorganica+Chimica+Acta%22">Inorganica Chimica Acta</searchLink>. May2026, Vol. 594, pN.PAG-N.PAG. 1p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Crystal+structure%22">Crystal structure</searchLink><br /><searchLink fieldCode="DE" term="%22Metal+complexes%22">Metal complexes</searchLink><br /><searchLink fieldCode="DE" term="%22Antibacterial+agents%22">Antibacterial agents</searchLink><br /><searchLink fieldCode="DE" term="%22Hydrazone+derivatives%22">Hydrazone derivatives</searchLink><br /><searchLink fieldCode="DE" term="%22Zinc%22">Zinc</searchLink><br /><searchLink fieldCode="DE" term="%22Materials+testing%22">Materials testing</searchLink><br /><searchLink fieldCode="DE" term="%22Copper%22">Copper</searchLink><br /><searchLink fieldCode="DE" term="%22Chemical+synthesis%22">Chemical synthesis</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: An aroylhydrazone compound N′ -(2-hydroxy-4-methoxybenzylidene)-3-methylbenzohydrazide (H 2 L) was prepared and characterized by IR, UV–Vis, 1H and 13C NMR spectra. Reaction of H 2 L with copper nitrate, cobalt nitrate and zinc iodide, respectively, afforded three new complexes [Cu 2 (HL) 2 (ONO 2) 2 ]∙2H 2 O (1 ∙2H 2 O), [Co 2 L 2 (EtOH) 2 (OH 2) 2 ]2NO 3 (2), and [Zn 2 I 2 (HL) 2 ]∙2EtOH (3 ∙2EtOH). The complexes have been characterized by IR and UV–Vis spectra. Structures of H 2 L and the complexes were further confirmed by single crystal X-ray determination. H 2 L crystallizes in monoclinic system space group P 2 1 / c , and the three complexes in triclinic P -1. Single crystal X-ray diffraction analysis reveals that the Cu atoms in 1 and Zn atoms in 3 are in square pyramidal coordination, and the Co atoms in 2 are in octahedral coordination. The compounds were assayed against the bacterial strains Bacillus subtillis , Staphylococcus aureus , Escherichia coli , and Pseudomonas aereuguinosa. The Cu and Zn complexes have effective antibacterial activities. [Display omitted] • The aroylhydrazone compound N′ -(2-hydroxy-4-methoxybenzylidene)-3-methylbenzohydrazide was newly synthesized. • The three complexes were newly synthesized. • Single crystal structures of the aroylhydrazone compound and the complexes were first reported. • The complexes have potential antibacterial activities on the bacterial strains Bacillus subtillis , Staphylococcus aureus , Escherichia coli , and Pseudomonas aereuguinosa. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Inorganica Chimica Acta is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ica.2026.123094 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: N.PAG Subjects: – SubjectFull: Crystal structure Type: general – SubjectFull: Metal complexes Type: general – SubjectFull: Antibacterial agents Type: general – SubjectFull: Hydrazone derivatives Type: general – SubjectFull: Zinc Type: general – SubjectFull: Materials testing Type: general – SubjectFull: Copper Type: general – SubjectFull: Chemical synthesis Type: general Titles: – TitleFull: Synthesis, characterization and crystal structures of N′-(2-hydroxy-4-methoxybenzylidene)-3-methylbenzohydrazide and it's copper(II), cobalt(III) and zinc(II) complexes with antibacterial activity. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Mao, Fu-Lin IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 00201693 Numbering: – Type: volume Value: 594 Titles: – TitleFull: Inorganica Chimica Acta Type: main |
| ResultId | 1 |
