Synthesis of discodermolide intermediates from engineered polyketides

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Bibliographic Details
Title: Synthesis of discodermolide intermediates from engineered polyketides
Authors: Burlingame, Mark A. burlingame@kosan.com, Mendoza, Esteban1, Ashley, Gary W.1, Myles, David C.1
Source: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Feb2006, Vol. 47 Issue 7, p1209-1211. 3p.
Subjects: Polyketides, Acrylonitrile, Cyclic compounds, Carbon compounds
Abstract: Abstract: Key intermediates used in Smith’s total synthesis of discodermolide were synthesized from an engineered polyketide made via precursor feeding to genetically modified polyketide producing bacteria. [Copyright &y& Elsevier]
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Database: Engineering Source
Description
Abstract:Abstract: Key intermediates used in Smith’s total synthesis of discodermolide were synthesized from an engineered polyketide made via precursor feeding to genetically modified polyketide producing bacteria. [Copyright &y& Elsevier]
ISSN:00404039
DOI:10.1016/j.tetlet.2005.12.010