View in EDS

Measurements of deposited dose with induced β+ activity in proton and heavy-ion therapy

Saved in:
Bibliographic Details
Title: Measurements of deposited dose with induced β+ activity in proton and heavy-ion therapy
Authors: Inaniwa, T.1 taku@nirs.go.jp, Kohno, T.1, Tomitani, T.2, Urakabe, E.3, Sato, S.2, Kanazawa, M.2, Kanai, T.2
Source: Nuclear Instruments & Methods in Physics Research Section A. Oct2007, Vol. 580 Issue 2, p1140-1143. 4p.
Subjects: Cancer treatment, Intermediates (Chemistry), Irradiation, Electrons
Abstract: Abstract: For the effective utilization of the favorable properties of heavy-ion beams in cancer treatment, it is important to evaluate the range of incident ions and the deposited dose distribution in a patient''s body. For this purpose, the utilization of positron emitters induced in therapeutic irradiation is, at present, the only feasible method for in situ and non-invasive monitoring of heavy-ion therapy. In this study, we performed irradiation experiments with three species of ions to a water target, and the annihilation gamma-ray distributions were obtained with a positron camera. We applied the maximum likelihood estimation (MLE) method for the detected distributions to derive the range of incident ions and the deposited dose distribution in the target. As a result, the ranges were determined with a difference between the MLE range R MLE and the experimental range R exp less than 1.1mm. The good agreement between the estimated dose distribution with the MLE method and the measured one implies that a deposited dose distribution in a target could be estimated from a detected annihilation gamma-ray distribution. [Copyright &y& Elsevier]
Copyright of Nuclear Instruments & Methods in Physics Research Section A is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 26585929
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Measurements of deposited dose with induced β<superscript>+</superscript> activity in proton and heavy-ion therapy
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Inaniwa%2C+T%2E%22">Inaniwa, T.</searchLink><relatesTo>1</relatesTo><i> taku@nirs.go.jp</i><br /><searchLink fieldCode="AR" term="%22Kohno%2C+T%2E%22">Kohno, T.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Tomitani%2C+T%2E%22">Tomitani, T.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Urakabe%2C+E%2E%22">Urakabe, E.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Sato%2C+S%2E%22">Sato, S.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Kanazawa%2C+M%2E%22">Kanazawa, M.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Kanai%2C+T%2E%22">Kanai, T.</searchLink><relatesTo>2</relatesTo>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Nuclear+Instruments+%26+Methods+in+Physics+Research+Section+A%22">Nuclear Instruments & Methods in Physics Research Section A</searchLink>. Oct2007, Vol. 580 Issue 2, p1140-1143. 4p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Cancer+treatment%22">Cancer treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Intermediates+%28Chemistry%29%22">Intermediates (Chemistry)</searchLink><br /><searchLink fieldCode="DE" term="%22Irradiation%22">Irradiation</searchLink><br /><searchLink fieldCode="DE" term="%22Electrons%22">Electrons</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Abstract: For the effective utilization of the favorable properties of heavy-ion beams in cancer treatment, it is important to evaluate the range of incident ions and the deposited dose distribution in a patient''s body. For this purpose, the utilization of positron emitters induced in therapeutic irradiation is, at present, the only feasible method for in situ and non-invasive monitoring of heavy-ion therapy. In this study, we performed irradiation experiments with three species of ions to a water target, and the annihilation gamma-ray distributions were obtained with a positron camera. We applied the maximum likelihood estimation (MLE) method for the detected distributions to derive the range of incident ions and the deposited dose distribution in the target. As a result, the ranges were determined with a difference between the MLE range R MLE and the experimental range R exp less than 1.1mm. The good agreement between the estimated dose distribution with the MLE method and the measured one implies that a deposited dose distribution in a target could be estimated from a detected annihilation gamma-ray distribution. [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Nuclear Instruments & Methods in Physics Research Section A is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=26585929
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.nima.2007.06.072
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 4
        StartPage: 1140
    Subjects:
      – SubjectFull: Cancer treatment
        Type: general
      – SubjectFull: Intermediates (Chemistry)
        Type: general
      – SubjectFull: Irradiation
        Type: general
      – SubjectFull: Electrons
        Type: general
    Titles:
      – TitleFull: Measurements of deposited dose with induced β+ activity in proton and heavy-ion therapy
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Inaniwa, T.
      – PersonEntity:
          Name:
            NameFull: Kohno, T.
      – PersonEntity:
          Name:
            NameFull: Tomitani, T.
      – PersonEntity:
          Name:
            NameFull: Urakabe, E.
      – PersonEntity:
          Name:
            NameFull: Sato, S.
      – PersonEntity:
          Name:
            NameFull: Kanazawa, M.
      – PersonEntity:
          Name:
            NameFull: Kanai, T.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: Oct2007
              Type: published
              Y: 2007
          Identifiers:
            – Type: issn-print
              Value: 01689002
          Numbering:
            – Type: volume
              Value: 580
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Nuclear Instruments & Methods in Physics Research Section A
              Type: main
ResultId 1