Extractive Spectrophotometric Methods for Determination of Zolmitriptan in Tablets.

Saved in:

Bibliographic Details
Title:	Extractive Spectrophotometric Methods for Determination of Zolmitriptan in Tablets.
Authors:	Aydogmus, Zeynep¹ aydogmus@itanbul.edu.tr, Inanli, Ipek¹
Source:	Journal of AOAC International. Sep/Oct2007, Vol. 90 Issue 5, p1237-1241. 5p. 3 Charts, 2 Graphs.
Subjects:	Spectrophotometry, Absorbance scale (Spectroscopy), Serotonin agonists, Drug tablets, Drug development, Research
Abstract:	The article presents the study on the accuracy and precision of the two simple and sensitive extractive spectrophotometric methods for the determination of zolmitriptan (ZTP) in tablets. The researchers developed the methods based on the formation of yellow ion-pair complexes between ZTP and tropaeolin OO and bromothymol blue in citrate-phosphate buffer. Statistical comparisons of the results reveal that the new methods show no significant differences in accuracy and precision.
Database:	Engineering Source

Description
Abstract:	The article presents the study on the accuracy and precision of the two simple and sensitive extractive spectrophotometric methods for the determination of zolmitriptan (ZTP) in tablets. The researchers developed the methods based on the formation of yellow ion-pair complexes between ZTP and tropaeolin OO and bromothymol blue in citrate-phosphate buffer. Statistical comparisons of the results reveal that the new methods show no significant differences in accuracy and precision.
ISSN:	10603271