Bibliographic Details
| Title: |
Base-Promoted Isomerization of cis-4-Formyl-2-azetidinones: Chemoselective C4-Epimerization vs... |
| Authors: |
Alcaide, Benito, Aly, Moustafa F. |
| Source: |
Journal of Organic Chemistry. 06/02/2000, Vol. 65 Issue 11, p3453. 7p. 9 Diagrams, 4 Charts. |
| Subjects: |
Lactams, Dimethylamine, Benzene, Phase-transfer catalysis, Rearrangements (Chemistry) |
| Abstract: |
Shows two simple, efficient and complementary methods for the regiospecific C4-epimerization of cis-4-formyl-2-azetidinones. Use of aqueous dimethylamine as reagent in heterogeneous medium with benzene; Presence of benzyltributylammonium bromide as the phase-transfer catalyst; Novel base-promoted rearrangement of the beta-lactam ring to cyclic enaminones. |
| Database: |
Engineering Source |
