Bibliographic Details
| Title: |
Construction of a Versatile High Precision Ambient Ionization Source for Direct Analysis and Imaging |
| Authors: |
Sampson, Jason S.1, Hawkridge, Adam M.1, Muddiman, David C. david_muddiman@ncsu.edu |
| Source: |
Journal of the American Society for Mass Spectrometry. Oct2008, Vol. 19 Issue 10, p1527-1534. 8p. |
| Subjects: |
Matrices (Mathematics), Biomolecules, Proteins, Lasers |
| Abstract: |
The design and construction of a high precision ambient ionization source matrix-assisted laser desorption electrospray ionization (MALDESI) are described in full detail, including a complete parts list. The computer controlled high precision motion control system and high repetition rate Explorer laser are demonstrated during MALDESI-FT-ICR analysis of peptides and proteins ranging from 1 to 17 kDa. The high stability ionization source platform described herein demonstrates both the advantages of the new MALDESI source and versatility for application to numerous desorption and ionization techniques. [Copyright &y& Elsevier] |
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| Database: |
Engineering Source |