Construction of a Versatile High Precision Ambient Ionization Source for Direct Analysis and Imaging
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| Title: | Construction of a Versatile High Precision Ambient Ionization Source for Direct Analysis and Imaging |
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| Authors: | Sampson, Jason S.1, Hawkridge, Adam M.1, Muddiman, David C. david_muddiman@ncsu.edu |
| Source: | Journal of the American Society for Mass Spectrometry. Oct2008, Vol. 19 Issue 10, p1527-1534. 8p. |
| Subjects: | Matrices (Mathematics), Biomolecules, Proteins, Lasers |
| Abstract: | The design and construction of a high precision ambient ionization source matrix-assisted laser desorption electrospray ionization (MALDESI) are described in full detail, including a complete parts list. The computer controlled high precision motion control system and high repetition rate Explorer laser are demonstrated during MALDESI-FT-ICR analysis of peptides and proteins ranging from 1 to 17 kDa. The high stability ionization source platform described herein demonstrates both the advantages of the new MALDESI source and versatility for application to numerous desorption and ionization techniques. [Copyright &y& Elsevier] |
| Copyright of Journal of the American Society for Mass Spectrometry is the property of American Chemical Society and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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