Incorporation of biotinylated manganese-salen complexes into streptavidin: New artificial metalloenzymes for enantioselective sulfoxidation
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| Title: | Incorporation of biotinylated manganese-salen complexes into streptavidin: New artificial metalloenzymes for enantioselective sulfoxidation |
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| Authors: | Pordea, A.1, Mathis, D.1, Ward, T.R.1,2 thomas.ward@unibas.ch |
| Source: | Journal of Organometallic Chemistry. Mar2009, Vol. 694 Issue 6, p930-936. 7p. |
| Subjects: | Metal complexes, Streptavidin, Metalloenzymes, Enantioselective catalysis, Oxidation, Ligands (Chemistry), Schiff bases |
| Abstract: | Abstract: Incorporation of achiral biotinylated manganese-salen complexes into streptavidin yields artificial metalloenzymes for aqueous sulfoxidation using hydrogen peroxide. Four biotinylated salen ligands were synthesized and their manganese complexes were tested in combination with several streptavidin mutants, yielding moderate conversions (up to 56%) and low enantioselectivities (maximum of 13% ee) for the sulfoxidation of thioanisole. [Copyright &y& Elsevier] |
| Copyright of Journal of Organometallic Chemistry is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 36779512 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Incorporation of biotinylated manganese-salen complexes into streptavidin: New artificial metalloenzymes for enantioselective sulfoxidation – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Pordea%2C+A%2E%22">Pordea, A.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Mathis%2C+D%2E%22">Mathis, D.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ward%2C+T%2ER%2E%22">Ward, T.R.</searchLink><relatesTo>1,2</relatesTo><i> thomas.ward@unibas.ch</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Organometallic+Chemistry%22">Journal of Organometallic Chemistry</searchLink>. Mar2009, Vol. 694 Issue 6, p930-936. 7p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Metal+complexes%22">Metal complexes</searchLink><br /><searchLink fieldCode="DE" term="%22Streptavidin%22">Streptavidin</searchLink><br /><searchLink fieldCode="DE" term="%22Metalloenzymes%22">Metalloenzymes</searchLink><br /><searchLink fieldCode="DE" term="%22Enantioselective+catalysis%22">Enantioselective catalysis</searchLink><br /><searchLink fieldCode="DE" term="%22Oxidation%22">Oxidation</searchLink><br /><searchLink fieldCode="DE" term="%22Ligands+%28Chemistry%29%22">Ligands (Chemistry)</searchLink><br /><searchLink fieldCode="DE" term="%22Schiff+bases%22">Schiff bases</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Abstract: Incorporation of achiral biotinylated manganese-salen complexes into streptavidin yields artificial metalloenzymes for aqueous sulfoxidation using hydrogen peroxide. Four biotinylated salen ligands were synthesized and their manganese complexes were tested in combination with several streptavidin mutants, yielding moderate conversions (up to 56%) and low enantioselectivities (maximum of 13% ee) for the sulfoxidation of thioanisole. [Copyright &y& Elsevier] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Organometallic Chemistry is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jorganchem.2008.11.023 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 930 Subjects: – SubjectFull: Metal complexes Type: general – SubjectFull: Streptavidin Type: general – SubjectFull: Metalloenzymes Type: general – SubjectFull: Enantioselective catalysis Type: general – SubjectFull: Oxidation Type: general – SubjectFull: Ligands (Chemistry) Type: general – SubjectFull: Schiff bases Type: general Titles: – TitleFull: Incorporation of biotinylated manganese-salen complexes into streptavidin: New artificial metalloenzymes for enantioselective sulfoxidation Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pordea, A. – PersonEntity: Name: NameFull: Mathis, D. – PersonEntity: Name: NameFull: Ward, T.R. IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 03 Text: Mar2009 Type: published Y: 2009 Identifiers: – Type: issn-print Value: 0022328X Numbering: – Type: volume Value: 694 – Type: issue Value: 6 Titles: – TitleFull: Journal of Organometallic Chemistry Type: main |
| ResultId | 1 |
