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Cellular Lipid Metabolism Is Influenced by the Coordination Environment of Copper.

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Title: Cellular Lipid Metabolism Is Influenced by the Coordination Environment of Copper.
Authors: Kennedy, David C.1, Lyn, Rodney K.1, Pezacki, John Paul1 John.Pezacki@nrc-cnrc.gc.ca
Source: Journal of the American Chemical Society. 2/25/2009, Vol. 131 Issue 7, p2444-2445. 2p. 1 Color Photograph, 1 Graph.
Subjects: Lipid metabolism, Copper, Liver cells, Raman effect, Microscopy, Cell metabolism
Abstract: The article presents a study which investigates the effect of the copper (Cu) species on lipid metabolism in liver cells. To observe the size and distribution of lipid bodies in liver cells, coherent anti-Strokes Raman scattering (CARS) microscopy is utilized. Findings suggest that only an excess of complexed Cu result in significant increase in lipid content in liver cells. It was also discovered that Cu overload results in rapid and dramatic increase in lipid body formation.
Database: Engineering Source
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  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 37143952
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Cellular Lipid Metabolism Is Influenced by the Coordination Environment of Copper.
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  Data: <searchLink fieldCode="AR" term="%22Kennedy%2C+David+C%2E%22">Kennedy, David C.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Lyn%2C+Rodney+K%2E%22">Lyn, Rodney K.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Pezacki%2C+John+Paul%22">Pezacki, John Paul</searchLink><relatesTo>1</relatesTo><i> John.Pezacki@nrc-cnrc.gc.ca</i>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+the+American+Chemical+Society%22">Journal of the American Chemical Society</searchLink>. 2/25/2009, Vol. 131 Issue 7, p2444-2445. 2p. 1 Color Photograph, 1 Graph.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Lipid+metabolism%22">Lipid metabolism</searchLink><br /><searchLink fieldCode="DE" term="%22Copper%22">Copper</searchLink><br /><searchLink fieldCode="DE" term="%22Liver+cells%22">Liver cells</searchLink><br /><searchLink fieldCode="DE" term="%22Raman+effect%22">Raman effect</searchLink><br /><searchLink fieldCode="DE" term="%22Microscopy%22">Microscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Cell+metabolism%22">Cell metabolism</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The article presents a study which investigates the effect of the copper (Cu) species on lipid metabolism in liver cells. To observe the size and distribution of lipid bodies in liver cells, coherent anti-Strokes Raman scattering (CARS) microscopy is utilized. Findings suggest that only an excess of complexed Cu result in significant increase in lipid content in liver cells. It was also discovered that Cu overload results in rapid and dramatic increase in lipid body formation.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=37143952
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1021/ja809451w
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 2
        StartPage: 2444
    Subjects:
      – SubjectFull: Lipid metabolism
        Type: general
      – SubjectFull: Copper
        Type: general
      – SubjectFull: Liver cells
        Type: general
      – SubjectFull: Raman effect
        Type: general
      – SubjectFull: Microscopy
        Type: general
      – SubjectFull: Cell metabolism
        Type: general
    Titles:
      – TitleFull: Cellular Lipid Metabolism Is Influenced by the Coordination Environment of Copper.
        Type: main
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            NameFull: Kennedy, David C.
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            NameFull: Lyn, Rodney K.
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            NameFull: Pezacki, John Paul
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            – D: 25
              M: 02
              Text: 2/25/2009
              Type: published
              Y: 2009
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              Value: 131
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              Value: 7
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            – TitleFull: Journal of the American Chemical Society
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