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The Multiple Layers of Ubiquitin-Dependent Cell Cycle Control.

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Title: The Multiple Layers of Ubiquitin-Dependent Cell Cycle Control.
Authors: Wickliffe, Katherine1, Williamson, Adam1, Lingyan Jin1, Rape, Michael1 mrape@berkeley.edu
Source: Chemical Reviews. Apr2009, Vol. 109 Issue 4, p1537-1548. 12p. 4 Black and White Photographs.
Subjects: Ubiquitin, Cancer cell proliferation, Cell proliferation, Cell cycle regulation, Protein research
Abstract: The article focuses on the key concepts which demonstrates how ubiquitination regulates cell cycle progression. It also discusses the impact of of misregulation to aberrant proliferation. It notes that ubiquitination plays an important role on the progression of cell cycle in all eukaryotes. Moreover, multiple layers of regulation from ubiquitin has great potential for future innovative approaches to combat cancer cells proliferation in a more specific and effective ways.
Database: Engineering Source
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Header DbId: egs
DbLabel: Engineering Source
An: 38328107
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: The Multiple Layers of Ubiquitin-Dependent Cell Cycle Control.
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  Data: <searchLink fieldCode="AR" term="%22Wickliffe%2C+Katherine%22">Wickliffe, Katherine</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Williamson%2C+Adam%22">Williamson, Adam</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Lingyan+Jin%22">Lingyan Jin</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Rape%2C+Michael%22">Rape, Michael</searchLink><relatesTo>1</relatesTo><i> mrape@berkeley.edu</i>
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  Data: <searchLink fieldCode="JN" term="%22Chemical+Reviews%22">Chemical Reviews</searchLink>. Apr2009, Vol. 109 Issue 4, p1537-1548. 12p. 4 Black and White Photographs.
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  Data: <searchLink fieldCode="DE" term="%22Ubiquitin%22">Ubiquitin</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+cell+proliferation%22">Cancer cell proliferation</searchLink><br /><searchLink fieldCode="DE" term="%22Cell+proliferation%22">Cell proliferation</searchLink><br /><searchLink fieldCode="DE" term="%22Cell+cycle+regulation%22">Cell cycle regulation</searchLink><br /><searchLink fieldCode="DE" term="%22Protein+research%22">Protein research</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The article focuses on the key concepts which demonstrates how ubiquitination regulates cell cycle progression. It also discusses the impact of of misregulation to aberrant proliferation. It notes that ubiquitination plays an important role on the progression of cell cycle in all eukaryotes. Moreover, multiple layers of regulation from ubiquitin has great potential for future innovative approaches to combat cancer cells proliferation in a more specific and effective ways.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=38328107
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1021/cr800414e
    Languages:
      – Code: eng
        Text: English
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      Pagination:
        PageCount: 12
        StartPage: 1537
    Subjects:
      – SubjectFull: Ubiquitin
        Type: general
      – SubjectFull: Cancer cell proliferation
        Type: general
      – SubjectFull: Cell proliferation
        Type: general
      – SubjectFull: Cell cycle regulation
        Type: general
      – SubjectFull: Protein research
        Type: general
    Titles:
      – TitleFull: The Multiple Layers of Ubiquitin-Dependent Cell Cycle Control.
        Type: main
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      – PersonEntity:
          Name:
            NameFull: Wickliffe, Katherine
      – PersonEntity:
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            NameFull: Williamson, Adam
      – PersonEntity:
          Name:
            NameFull: Lingyan Jin
      – PersonEntity:
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            NameFull: Rape, Michael
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            – D: 01
              M: 04
              Text: Apr2009
              Type: published
              Y: 2009
          Identifiers:
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              Value: 00092665
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              Value: 109
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              Value: 4
          Titles:
            – TitleFull: Chemical Reviews
              Type: main
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