ALPHA-LINOLENIC ACID AND LINOLEIC ACID IN SERUM AND TISSUES AFTER FLAXSEED ( Linum usitatissimum) OIL IN VIVO ADMINISTRATION.
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| Title: | ALPHA-LINOLENIC ACID AND LINOLEIC ACID IN SERUM AND TISSUES AFTER FLAXSEED ( Linum usitatissimum) OIL IN VIVO ADMINISTRATION. |
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| Authors: | AVALLONE, ROSSELLA1 rossella.avallone@unimore.it, RUSTICHELLI, CECILIA2, CAMPIOLI, ENRICO1, NOTARANGELO, FRANCESCA MARIA PIA1, BRAGHIROLI, DANIELA2, BARALDI, MARIO1 |
| Source: | Journal of Food Lipids. Aug2009, Vol. 16 Issue 3, p287-296. 10p. 2 Charts, 2 Graphs. |
| Subjects: | Linolenic acids, Serum, Tissues, Flaxseed, Essential fatty acids |
| Abstract: | Essential fatty acids can be helpful in the prevention of several pathologies. The bioavailability of acute supplementation of different doses of flaxseed oil was studied by analyzing the level of alpha-linolenic acid (ALA) and linoleic acid (LA) in serum and tissues (adipose, liver) of rats tested at 2, 4, 8 and 16 h after the administration. The amount of flaxseed oil administered at increasing doses corresponded to 1, 2.5 and 5 g ALA/kg of body weight. The corresponding fatty acid methyl esters obtained via direct methylation were quantified using gas chromatography/mass spectrometry. Serum ALA level increased after 1 or 2.5 g/kg. ALA was increased in both adipose and liver tissue 4 h after the administration of 1 g/kg of flaxseed oil. There was no further increase by using a higher oil dosage. LA did not change in serum at the doses used. PRACTICAL APPLICATIONS The bioavailability of acute supplementation of increasing doses of flaxseed oil was examined by analyzing the level of alpha-linolenic acid (ALA) (ω3) and linoleic acid (ω6) in serum and tissues (adipose, liver).These data suggest that there is a limiting step in the absorption of these fatty acids and that there is no advantage to take more than 1 g/kg of ALA supplementation. The daily use of flaxseed oil could be a good alternative in some cases to fish oil in the prevention of several pathologies. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Food Lipids is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 43538521 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: ALPHA-LINOLENIC ACID AND LINOLEIC ACID IN SERUM AND TISSUES AFTER FLAXSEED ( Linum usitatissimum) OIL IN VIVO ADMINISTRATION. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22AVALLONE%2C+ROSSELLA%22">AVALLONE, ROSSELLA</searchLink><relatesTo>1</relatesTo><i> rossella.avallone@unimore.it</i><br /><searchLink fieldCode="AR" term="%22RUSTICHELLI%2C+CECILIA%22">RUSTICHELLI, CECILIA</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22CAMPIOLI%2C+ENRICO%22">CAMPIOLI, ENRICO</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22NOTARANGELO%2C+FRANCESCA+MARIA+PIA%22">NOTARANGELO, FRANCESCA MARIA PIA</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22BRAGHIROLI%2C+DANIELA%22">BRAGHIROLI, DANIELA</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22BARALDI%2C+MARIO%22">BARALDI, MARIO</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Food+Lipids%22">Journal of Food Lipids</searchLink>. Aug2009, Vol. 16 Issue 3, p287-296. 10p. 2 Charts, 2 Graphs. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Linolenic+acids%22">Linolenic acids</searchLink><br /><searchLink fieldCode="DE" term="%22Serum%22">Serum</searchLink><br /><searchLink fieldCode="DE" term="%22Tissues%22">Tissues</searchLink><br /><searchLink fieldCode="DE" term="%22Flaxseed%22">Flaxseed</searchLink><br /><searchLink fieldCode="DE" term="%22Essential+fatty+acids%22">Essential fatty acids</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Essential fatty acids can be helpful in the prevention of several pathologies. The bioavailability of acute supplementation of different doses of flaxseed oil was studied by analyzing the level of alpha-linolenic acid (ALA) and linoleic acid (LA) in serum and tissues (adipose, liver) of rats tested at 2, 4, 8 and 16 h after the administration. The amount of flaxseed oil administered at increasing doses corresponded to 1, 2.5 and 5 g ALA/kg of body weight. The corresponding fatty acid methyl esters obtained via direct methylation were quantified using gas chromatography/mass spectrometry. Serum ALA level increased after 1 or 2.5 g/kg. ALA was increased in both adipose and liver tissue 4 h after the administration of 1 g/kg of flaxseed oil. There was no further increase by using a higher oil dosage. LA did not change in serum at the doses used. PRACTICAL APPLICATIONS The bioavailability of acute supplementation of increasing doses of flaxseed oil was examined by analyzing the level of alpha-linolenic acid (ALA) (ω3) and linoleic acid (ω6) in serum and tissues (adipose, liver).These data suggest that there is a limiting step in the absorption of these fatty acids and that there is no advantage to take more than 1 g/kg of ALA supplementation. The daily use of flaxseed oil could be a good alternative in some cases to fish oil in the prevention of several pathologies. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Food Lipids is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/j.1745-4522.2009.01147.x Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 287 Subjects: – SubjectFull: Linolenic acids Type: general – SubjectFull: Serum Type: general – SubjectFull: Tissues Type: general – SubjectFull: Flaxseed Type: general – SubjectFull: Essential fatty acids Type: general Titles: – TitleFull: ALPHA-LINOLENIC ACID AND LINOLEIC ACID IN SERUM AND TISSUES AFTER FLAXSEED ( Linum usitatissimum) OIL IN VIVO ADMINISTRATION. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: AVALLONE, ROSSELLA – PersonEntity: Name: NameFull: RUSTICHELLI, CECILIA – PersonEntity: Name: NameFull: CAMPIOLI, ENRICO – PersonEntity: Name: NameFull: NOTARANGELO, FRANCESCA MARIA PIA – PersonEntity: Name: NameFull: BRAGHIROLI, DANIELA – PersonEntity: Name: NameFull: BARALDI, MARIO IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: Aug2009 Type: published Y: 2009 Identifiers: – Type: issn-print Value: 10657258 Numbering: – Type: volume Value: 16 – Type: issue Value: 3 Titles: – TitleFull: Journal of Food Lipids Type: main |
| ResultId | 1 |
