Bibliographic Details
| Title: |
nDEP microwells for single-cell patterning in physiological media. |
| Authors: |
MittalThese authors contributed equally to this work., Nikhil1, Rosenthal, Adam2,3, Voldman, Joel2 |
| Source: |
Lab on a Chip. Aug2007, Vol. 7 Issue 9, p1146-1153. 8p. |
| Subjects: |
Cell aggregation, Dielectrophoresis, Cell adhesion, Biocompatibility, Cell proliferation, Cell membranes, Morphology |
| Abstract: |
We present a novel technique to accurately position single cells on a substrate using negative dielectrophoresis and cell–substrate adhesion. The cells are suspended in physiological media throughout the patterning process. We also verify the biocompatibility of this method by demonstrating that the patterned cells proliferate and show normal morphology. We calculate the temperatures and transmembrane potential that cells in the device experience and compare them to physiologically acceptable levels described in previous studies. [ABSTRACT FROM AUTHOR] |
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| Database: |
Engineering Source |
