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Fast-neutron dose evaluation in BNCT with Fricke gel layer detectors

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Title: Fast-neutron dose evaluation in BNCT with Fricke gel layer detectors
Authors: Gambarini, G.1,2 grazia.gambarini@mi.infn.it, Bartesaghi, G.1,2, Burian, J.3, Carrara, M.4 mauro.carrara@istitutotumori.mi.it, Marek, M.3, Negri, A.1,2, Pirola, L.1, Viererbl, L.3
Source: Radiation Measurements. Dec2010, Vol. 45 Issue 10, p1398-1401. 4p.
Subjects: Radiation dosimetry, Boron-neutron capture therapy, Neutron sources, Cancer radiotherapy, Thermal neutron beams, Photons, Thermoluminescence
Abstract: Abstract: Boron neutron capture therapy (BNCT) is a cancer radiotherapy that uses epithermal and thermal neutron beams. The determination of the absorbed dose in healthy tissue, separating the various dose contributions having different radiobiological effectiveness (RBE) is of great importance for therapy planning. However, a standard code of practice has not yet been established because suitable methods for dosimetry in BNCT are still in progress. A study about the characterization of the epithermal column of the LVR-15 research reactor in Řež (CZ) has been performed, in particular concerning the fast-neutron dose. This dose is not negligible and its determination is important owing to its high RBE. Fast-neutron and photon dose distributions in a water phantom have been measured by means of Fricke gel layer dosimeters. Even if gel layer dosimetry is not yet standardized, it is presently the only method for obtaining images of each dose contribution in BNCT neutron fields. The results were compared with values measured with thermoluminescence detectors, twin ionization chambers data taken from literature and Monte Carlo simulations. [ABSTRACT FROM AUTHOR]
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Database: Engineering Source
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Abstract:Abstract: Boron neutron capture therapy (BNCT) is a cancer radiotherapy that uses epithermal and thermal neutron beams. The determination of the absorbed dose in healthy tissue, separating the various dose contributions having different radiobiological effectiveness (RBE) is of great importance for therapy planning. However, a standard code of practice has not yet been established because suitable methods for dosimetry in BNCT are still in progress. A study about the characterization of the epithermal column of the LVR-15 research reactor in Řež (CZ) has been performed, in particular concerning the fast-neutron dose. This dose is not negligible and its determination is important owing to its high RBE. Fast-neutron and photon dose distributions in a water phantom have been measured by means of Fricke gel layer dosimeters. Even if gel layer dosimetry is not yet standardized, it is presently the only method for obtaining images of each dose contribution in BNCT neutron fields. The results were compared with values measured with thermoluminescence detectors, twin ionization chambers data taken from literature and Monte Carlo simulations. [ABSTRACT FROM AUTHOR]
ISSN:13504487
DOI:10.1016/j.radmeas.2010.05.004