Bibliographic Details
| Title: |
A New Synthesis of NeufAc from D-Glucono-σ-lactone. |
| Authors: |
Ke-Gang Liu, Shi Yan, Yu-Lin Wu, Zhu-Jun Yao |
| Source: |
Journal of Organic Chemistry. 9/20/2002, Vol. 67 Issue 19, p6758. 6p. 5 Diagrams. |
| Subjects: |
Methyl groups, Esters, Lactones |
| Abstract: |
A new route to Neu5Ac methyl ester (23) with a readily available sugar D-glucono-δ-lactone as starting material has been developed. A diastereoselective propargylation of α-acetamino aldehyde and a subsequent KMnO[sub 4] oxidation of the terminal alkyne served as the key steps. [ABSTRACT FROM AUTHOR] |
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| Database: |
Engineering Source |
