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Hookerolides A–D, the first naturally occurring C17-pseudoguaianolides from Inula hookeri

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Title: Hookerolides A–D, the first naturally occurring C17-pseudoguaianolides from Inula hookeri
Authors: Cheng, Xiang-Rong1,2, Ren, Jie1, Wang, Chun-Hui1, Guan, Bin1, Qin, Jiang-Jiang1, Yan, Shi-Kai1, Jin, Hui-Zi1 kimhz@sjtu.edu.cn, Zhang, Wei-Dong1,3 wdzhangy@hotmail.com
Source: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Apr2013, Vol. 54 Issue 15, p1943-1946. 4p.
Subjects: Carbon isotopes, Pseudoguaianolides, Chemical structure, Nuclear magnetic resonance spectroscopy, Cell-mediated cytotoxicity, Anti-inflammatory agents
Abstract: Abstract: Four unprecedented C17-pseudoguaianolides with extended side chains, hookerolides A–D (1–4), were isolated from the whole plants of Inula hookeri. Their structures and absolute configurations were elucidated by a combination of NMR spectroscopy, CD spectrum, and the modified Mosher method. The in vitro bioactivity evaluation suggested that 1–4 possessed moderate to weak anti-inflammatory and cytotoxic properties. [Copyright &y& Elsevier]
Copyright of Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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Header DbId: egs
DbLabel: Engineering Source
An: 86155998
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Hookerolides A–D, the first naturally occurring C<subscript>17</subscript>-pseudoguaianolides from Inula hookeri
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  Data: <searchLink fieldCode="AR" term="%22Cheng%2C+Xiang-Rong%22">Cheng, Xiang-Rong</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Ren%2C+Jie%22">Ren, Jie</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Wang%2C+Chun-Hui%22">Wang, Chun-Hui</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Guan%2C+Bin%22">Guan, Bin</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Qin%2C+Jiang-Jiang%22">Qin, Jiang-Jiang</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Yan%2C+Shi-Kai%22">Yan, Shi-Kai</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Jin%2C+Hui-Zi%22">Jin, Hui-Zi</searchLink><relatesTo>1</relatesTo><i> kimhz@sjtu.edu.cn</i><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Wei-Dong%22">Zhang, Wei-Dong</searchLink><relatesTo>1,3</relatesTo><i> wdzhangy@hotmail.com</i>
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  Data: <searchLink fieldCode="JN" term="%22Tetrahedron+Letters%3A+International+Organ+for+the+Rapid+Publication+of+Preliminary+Communications+in+Organic+Chemistry%22">Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry</searchLink>. Apr2013, Vol. 54 Issue 15, p1943-1946. 4p.
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  Data: <searchLink fieldCode="DE" term="%22Carbon+isotopes%22">Carbon isotopes</searchLink><br /><searchLink fieldCode="DE" term="%22Pseudoguaianolides%22">Pseudoguaianolides</searchLink><br /><searchLink fieldCode="DE" term="%22Chemical+structure%22">Chemical structure</searchLink><br /><searchLink fieldCode="DE" term="%22Nuclear+magnetic+resonance+spectroscopy%22">Nuclear magnetic resonance spectroscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Cell-mediated+cytotoxicity%22">Cell-mediated cytotoxicity</searchLink><br /><searchLink fieldCode="DE" term="%22Anti-inflammatory+agents%22">Anti-inflammatory agents</searchLink>
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  Label: Abstract
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  Data: Abstract: Four unprecedented C17-pseudoguaianolides with extended side chains, hookerolides A–D (1–4), were isolated from the whole plants of Inula hookeri. Their structures and absolute configurations were elucidated by a combination of NMR spectroscopy, CD spectrum, and the modified Mosher method. The in vitro bioactivity evaluation suggested that 1–4 possessed moderate to weak anti-inflammatory and cytotoxic properties. [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1016/j.tetlet.2013.01.116
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      – Code: eng
        Text: English
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        StartPage: 1943
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      – SubjectFull: Carbon isotopes
        Type: general
      – SubjectFull: Pseudoguaianolides
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      – SubjectFull: Chemical structure
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      – SubjectFull: Nuclear magnetic resonance spectroscopy
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      – SubjectFull: Cell-mediated cytotoxicity
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      – SubjectFull: Anti-inflammatory agents
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      – TitleFull: Hookerolides A–D, the first naturally occurring C17-pseudoguaianolides from Inula hookeri
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            NameFull: Cheng, Xiang-Rong
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            NameFull: Ren, Jie
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              Text: Apr2013
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              Y: 2013
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