Bibliographic Details
| Title: |
Reversible sporicidal action of cuprous ions. |
| Authors: |
Rutherford, G C, Marquis, R E |
| Source: |
Journal of Industrial Microbiology & Biotechnology. Apr97, Vol. 18 Issue 4, p223. 3p. |
| Subjects: |
Ions, Copper poisoning |
| Abstract: |
At 10 mM, Cu[SUP+] was highly protective against killing of spores of Bacillus megaterium (ATCC 19213 by H[SUB2]O[SUB2], while at higher concentrations, from 15-100 mM, killing was augmented. In contrast, Cu[SUP2+], Fe[SUP2+], Fe[SUP3+], Co[SUP2+] or Co[SUP3+] ions acted only protectively. Cu[SUP+] itself was sporicidal in the absence of H[SUB2]O[SUB2] or ascorbate, and its sporicidal action did not depend on generation of highly reactive oxygen species. It appeared that killing involved either inhibition of germination or copper toxicity to germinated cells in that Cu[SUB+]-inactivated spores did not germinate readily but chemical decoating of the cells prior to plating on a solid medium resulted in reversal of the sporicidal effect. [ABSTRACT FROM AUTHOR] |
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| Database: |
Engineering Source |
