Bibliographic Details
| Title: |
Simultaneous determination of pregnenolone sulphate, dehydroepiandrosterone and allopregnanolone in rat brain areas by liquid chromatography–electrospray tandem mass spectrometry. |
| Authors: |
Rustichelli, Cecilia1 cecilia.rustichelli@unimore.it, Pinetti, Diego2 diego.pinetti@unimore.it, Lucchi, Chiara3 chiara.lucchi@unimore.it, Ravazzini, Federica4 f.ravazzini@hotmail.it, Puia, Giulia4 giulia.puja@unimore.it |
| Source: |
Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences. Jul2013, Vol. 930, p62-69. 8p. |
| Subjects: |
Pregnenolone, Sulfates, Dehydroepiandrosterone, Pregnanolone, Brain anatomy, Liquid chromatography-mass spectrometry, Laboratory rats |
| Abstract: |
Highlights: [•] We developed a LC/MS/MS quantitatation of PS, DHEA and AP levels in different rat brain areas. [•] The sample processing enables the recovery of free and sulphate steroids from brain samples. [•] For the first time pregnenolone sulphate has been quantified in rat brain samples. [•] The proposed method can be successfully applied in neuropharmacological studies. [Copyright &y& Elsevier] |
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Copyright of Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Engineering Source |
