Synthesis of PHB-based carrier for drug delivery systems with pH-controlled release.

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Title: Synthesis of PHB-based carrier for drug delivery systems with pH-controlled release.
Authors: Michalak, Michał1, Marek, Adam A.2, Zawadiak, Jan2, Kawalec, Michał1, Kurcok, Piotr1 piotr.kurcok@cmpw-pan.edu.pl
Source: European Polymer Journal. Dec2013, Vol. 49 Issue 12, p4149-4156. 8p.
Subjects: Poly-beta-hydroxybutyrate, Fatty acid synthesis, Drug delivery systems, pH effect, Bioconjugates, Amines
Abstract: Highlights: [•] Selective transformation of PHB crotonate into PHB glyoxylate via ozonolysis. [•] Model drug delivery system – conjugate of PHB glyoxylate with primary amine. [•] pH-controlled release of amine from the model conjugate. [Copyright &y& Elsevier]
Copyright of European Polymer Journal is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
An: 92502938
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PubTypeId: academicJournal
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  Data: Synthesis of PHB-based carrier for drug delivery systems with pH-controlled release.
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  Data: <searchLink fieldCode="AR" term="%22Michalak%2C+Michał%22">Michalak, Michał</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Marek%2C+Adam+A%2E%22">Marek, Adam A.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Zawadiak%2C+Jan%22">Zawadiak, Jan</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Kawalec%2C+Michał%22">Kawalec, Michał</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Kurcok%2C+Piotr%22">Kurcok, Piotr</searchLink><relatesTo>1</relatesTo><i> piotr.kurcok@cmpw-pan.edu.pl</i>
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  Data: <searchLink fieldCode="JN" term="%22European+Polymer+Journal%22">European Polymer Journal</searchLink>. Dec2013, Vol. 49 Issue 12, p4149-4156. 8p.
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  Data: <searchLink fieldCode="DE" term="%22Poly-beta-hydroxybutyrate%22">Poly-beta-hydroxybutyrate</searchLink><br /><searchLink fieldCode="DE" term="%22Fatty+acid+synthesis%22">Fatty acid synthesis</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+delivery+systems%22">Drug delivery systems</searchLink><br /><searchLink fieldCode="DE" term="%22pH+effect%22">pH effect</searchLink><br /><searchLink fieldCode="DE" term="%22Bioconjugates%22">Bioconjugates</searchLink><br /><searchLink fieldCode="DE" term="%22Amines%22">Amines</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Highlights: [•] Selective transformation of PHB crotonate into PHB glyoxylate via ozonolysis. [•] Model drug delivery system – conjugate of PHB glyoxylate with primary amine. [•] pH-controlled release of amine from the model conjugate. [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of European Polymer Journal is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.eurpolymj.2013.09.021
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      – Code: eng
        Text: English
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        PageCount: 8
        StartPage: 4149
    Subjects:
      – SubjectFull: Poly-beta-hydroxybutyrate
        Type: general
      – SubjectFull: Fatty acid synthesis
        Type: general
      – SubjectFull: Drug delivery systems
        Type: general
      – SubjectFull: pH effect
        Type: general
      – SubjectFull: Bioconjugates
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      – SubjectFull: Amines
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      – TitleFull: Synthesis of PHB-based carrier for drug delivery systems with pH-controlled release.
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              M: 12
              Text: Dec2013
              Type: published
              Y: 2013
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