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Bioactive eudesmane and germacrane derivatives from Inula wissmanniana Hand.-Mazz.

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Title: Bioactive eudesmane and germacrane derivatives from Inula wissmanniana Hand.-Mazz.
Authors: Cheng, Xiang-Rong1,2, Zhang, Shou-De3, Wang, Chun-Hui1, Ren, Jie1, Qin, Jiang-Jiang1, Tang, Xue2, Shen, Yun-Heng4, Yan, Shi-Kai1, Jin, Hui-Zi1 kimhz@sjtu.edu.cn, Zhang, Wei-Dong1,4 wdzhangy@hotmail.com
Source: Phytochemistry. Dec2013, Vol. 96, p214-222. 9p.
Subjects: Bioactive compounds, Eudesmanes derivatives, Sesquiterpenes, Inulase, Stereochemistry, Macrophages, Cell-mediated cytotoxicity
Abstract: Highlights: [•] 12 New and 9 known eudesmanes and germacranes were isolated from the whole plants of I. wissmanniana. [•] Rare 4,5-secoeudesmane, 3,4-secoeudesmane, and eudesman-12,5-olides were elucidated. [•] Unusual germacra-4-en-12,6-olides were reported as well. [•] ECD and X-ray analyses were applied to determine the absolute stereochemistry of new isolates. [•] Some isolates exhibited strong NO inhibition in macrophages and cytotoxicity in tumor cells. [Copyright &y& Elsevier]
Copyright of Phytochemistry is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 92515454
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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Items – Name: Title
  Label: Title
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  Data: Bioactive eudesmane and germacrane derivatives from Inula wissmanniana Hand.-Mazz.
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  Label: Authors
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  Data: <searchLink fieldCode="AR" term="%22Cheng%2C+Xiang-Rong%22">Cheng, Xiang-Rong</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Shou-De%22">Zhang, Shou-De</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Wang%2C+Chun-Hui%22">Wang, Chun-Hui</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ren%2C+Jie%22">Ren, Jie</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Qin%2C+Jiang-Jiang%22">Qin, Jiang-Jiang</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Tang%2C+Xue%22">Tang, Xue</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Shen%2C+Yun-Heng%22">Shen, Yun-Heng</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Yan%2C+Shi-Kai%22">Yan, Shi-Kai</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Jin%2C+Hui-Zi%22">Jin, Hui-Zi</searchLink><relatesTo>1</relatesTo><i> kimhz@sjtu.edu.cn</i><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Wei-Dong%22">Zhang, Wei-Dong</searchLink><relatesTo>1,4</relatesTo><i> wdzhangy@hotmail.com</i>
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  Data: <searchLink fieldCode="JN" term="%22Phytochemistry%22">Phytochemistry</searchLink>. Dec2013, Vol. 96, p214-222. 9p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Bioactive+compounds%22">Bioactive compounds</searchLink><br /><searchLink fieldCode="DE" term="%22Eudesmanes+derivatives%22">Eudesmanes derivatives</searchLink><br /><searchLink fieldCode="DE" term="%22Sesquiterpenes%22">Sesquiterpenes</searchLink><br /><searchLink fieldCode="DE" term="%22Inulase%22">Inulase</searchLink><br /><searchLink fieldCode="DE" term="%22Stereochemistry%22">Stereochemistry</searchLink><br /><searchLink fieldCode="DE" term="%22Macrophages%22">Macrophages</searchLink><br /><searchLink fieldCode="DE" term="%22Cell-mediated+cytotoxicity%22">Cell-mediated cytotoxicity</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Highlights: [•] 12 New and 9 known eudesmanes and germacranes were isolated from the whole plants of I. wissmanniana. [•] Rare 4,5-secoeudesmane, 3,4-secoeudesmane, and eudesman-12,5-olides were elucidated. [•] Unusual germacra-4-en-12,6-olides were reported as well. [•] ECD and X-ray analyses were applied to determine the absolute stereochemistry of new isolates. [•] Some isolates exhibited strong NO inhibition in macrophages and cytotoxicity in tumor cells. [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Phytochemistry is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=92515454
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.phytochem.2013.10.006
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 9
        StartPage: 214
    Subjects:
      – SubjectFull: Bioactive compounds
        Type: general
      – SubjectFull: Eudesmanes derivatives
        Type: general
      – SubjectFull: Sesquiterpenes
        Type: general
      – SubjectFull: Inulase
        Type: general
      – SubjectFull: Stereochemistry
        Type: general
      – SubjectFull: Macrophages
        Type: general
      – SubjectFull: Cell-mediated cytotoxicity
        Type: general
    Titles:
      – TitleFull: Bioactive eudesmane and germacrane derivatives from Inula wissmanniana Hand.-Mazz.
        Type: main
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            NameFull: Cheng, Xiang-Rong
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            NameFull: Zhang, Shou-De
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            NameFull: Wang, Chun-Hui
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            NameFull: Ren, Jie
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            NameFull: Qin, Jiang-Jiang
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            NameFull: Tang, Xue
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            NameFull: Shen, Yun-Heng
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            NameFull: Yan, Shi-Kai
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            NameFull: Jin, Hui-Zi
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            NameFull: Zhang, Wei-Dong
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          Dates:
            – D: 01
              M: 12
              Text: Dec2013
              Type: published
              Y: 2013
          Identifiers:
            – Type: issn-print
              Value: 00319422
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              Value: 96
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            – TitleFull: Phytochemistry
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