Cytokine regulation of neuronal differentiation of hippocampal progenitor cells.

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Bibliographic Details
Title: Cytokine regulation of neuronal differentiation of hippocampal progenitor cells.
Authors: Mehler, Mark F., Rozental, Renato
Source: Nature. 3/4/1993, Vol. 362 Issue 6415, p62. 4p. 6 Black and White Photographs, 2 Charts, 9 Graphs.
Subjects: Biochemistry
Abstract: Investigates the evolutionary connection of the signaling mechanisms governing hematolymphopoiesis and those regulating neural development using retroviral transduction of a temperature-sensitive mutant form of the SV40 large T antigen to develop conditionally immortalized murine embryonic hippocampal progenitor cell lines. Morphological and immunocytochemical indices of progressive neuronal maturation; Electrophysiological characteristics of cultured cells.
Database: Engineering Source
Description
Abstract:Investigates the evolutionary connection of the signaling mechanisms governing hematolymphopoiesis and those regulating neural development using retroviral transduction of a temperature-sensitive mutant form of the SV40 large T antigen to develop conditionally immortalized murine embryonic hippocampal progenitor cell lines. Morphological and immunocytochemical indices of progressive neuronal maturation; Electrophysiological characteristics of cultured cells.
ISSN:00280836
DOI:10.1038/362062a0