Bibliographic Details
| Title: |
Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain... |
| Authors: |
Burke Jr., Terrence R., Smith, Mark S. |
| Source: |
Biochemistry. 5/31/94, Vol. 33 Issue 21, p6490. 5p. 6 Graphs. |
| Subjects: |
Peptides, Phosphatases |
| Abstract: |
Describes the development of Src homology 2 (SH2) inhibitory peptides containing phosphatase-resistant phosphotyrosyl (pTyr) surrogates. SH2 domain inhibitor design; Phosphonopeptide binding; Sensitivity to phosphatases. |
| Database: |
Engineering Source |