Asymmetric formation of quaternary centers through aza-annulation of chiral beta-enamino esters...

Saved in:
Bibliographic Details
Title: Asymmetric formation of quaternary centers through aza-annulation of chiral beta-enamino esters...
Authors: Barta, Nancy S., Brode, Adam
Source: Journal of the American Chemical Society. 7/13/94, Vol. 116 Issue 14, p6201. 6p. 3 Diagrams, 3 Charts.
Subjects: Chirality, Stereochemistry
Abstract: Discusses the stereoselective formation of quaternary carbon centers through the aza-annulation of beta-enamino ester substrates with acrylate derivatives. Generation of tetrasubstituted secondary enamines from the optically active primary amine (R)-alpha-phenethylamine and the alpha-amino esters of L-valine and (R)-phenylglycine.
Database: Engineering Source
Description
Abstract:Discusses the stereoselective formation of quaternary carbon centers through the aza-annulation of beta-enamino ester substrates with acrylate derivatives. Generation of tetrasubstituted secondary enamines from the optically active primary amine (R)-alpha-phenethylamine and the alpha-amino esters of L-valine and (R)-phenylglycine.
ISSN:00027863
DOI:10.1021/ja00093a020