Bibliographic Details
| Title: |
A concise synthesis of the differentiating antibiotic L-azatyrosine. |
| Authors: |
Ye, Bin, Burke Jr., Terrence R. |
| Source: |
Journal of Organic Chemistry. 4/21/95, Vol. 60 Issue 8, p2640. 2p. 4 Diagrams. |
| Subjects: |
Alanine, Antibiotics, Biosynthesis |
| Abstract: |
Describes the development of an enantiospecific synthesis of the antibiotic L-beta-(5-hydroxy-2-pyridyl)alanine (L-azatyrosine) from 3-hydroxypyridine using a convergent route that is amenable to large scale preparation of the antibiotic in optically pure form. Natural source of azatyrosine; Therapeutic usage; Mechanism of synthesis. |
| Database: |
Engineering Source |
