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A concise synthesis of the differentiating antibiotic L-azatyrosine.

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Title: A concise synthesis of the differentiating antibiotic L-azatyrosine.
Authors: Ye, Bin, Burke Jr., Terrence R.
Source: Journal of Organic Chemistry. 4/21/95, Vol. 60 Issue 8, p2640. 2p. 4 Diagrams.
Subjects: Alanine, Antibiotics, Biosynthesis
Abstract: Describes the development of an enantiospecific synthesis of the antibiotic L-beta-(5-hydroxy-2-pyridyl)alanine (L-azatyrosine) from 3-hydroxypyridine using a convergent route that is amenable to large scale preparation of the antibiotic in optically pure form. Natural source of azatyrosine; Therapeutic usage; Mechanism of synthesis.
Database: Engineering Source
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  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 9507211834
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: A concise synthesis of the differentiating antibiotic L-azatyrosine.
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  Data: <searchLink fieldCode="AR" term="%22Ye%2C+Bin%22">Ye, Bin</searchLink><br /><searchLink fieldCode="AR" term="%22Burke+Jr%2E%2C+Terrence+R%2E%22">Burke Jr., Terrence R.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Organic+Chemistry%22">Journal of Organic Chemistry</searchLink>. 4/21/95, Vol. 60 Issue 8, p2640. 2p. 4 Diagrams.
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  Data: <searchLink fieldCode="DE" term="%22Alanine%22">Alanine</searchLink><br /><searchLink fieldCode="DE" term="%22Antibiotics%22">Antibiotics</searchLink><br /><searchLink fieldCode="DE" term="%22Biosynthesis%22">Biosynthesis</searchLink>
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  Label: Abstract
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  Data: Describes the development of an enantiospecific synthesis of the antibiotic L-beta-(5-hydroxy-2-pyridyl)alanine (L-azatyrosine) from 3-hydroxypyridine using a convergent route that is amenable to large scale preparation of the antibiotic in optically pure form. Natural source of azatyrosine; Therapeutic usage; Mechanism of synthesis.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=9507211834
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1021/jo00113a056
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 2
        StartPage: 2640
    Subjects:
      – SubjectFull: Alanine
        Type: general
      – SubjectFull: Antibiotics
        Type: general
      – SubjectFull: Biosynthesis
        Type: general
    Titles:
      – TitleFull: A concise synthesis of the differentiating antibiotic L-azatyrosine.
        Type: main
  BibRelationships:
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      – PersonEntity:
          Name:
            NameFull: Ye, Bin
      – PersonEntity:
          Name:
            NameFull: Burke Jr., Terrence R.
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          Dates:
            – D: 21
              M: 04
              Text: 4/21/95
              Type: published
              Y: 1995
          Identifiers:
            – Type: issn-print
              Value: 00223263
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            – Type: volume
              Value: 60
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: Journal of Organic Chemistry
              Type: main
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