A concise synthesis of the differentiating antibiotic L-azatyrosine.
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| Title: | A concise synthesis of the differentiating antibiotic L-azatyrosine. |
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| Authors: | Ye, Bin, Burke Jr., Terrence R. |
| Source: | Journal of Organic Chemistry. 4/21/95, Vol. 60 Issue 8, p2640. 2p. 4 Diagrams. |
| Subjects: | Alanine, Antibiotics, Biosynthesis |
| Abstract: | Describes the development of an enantiospecific synthesis of the antibiotic L-beta-(5-hydroxy-2-pyridyl)alanine (L-azatyrosine) from 3-hydroxypyridine using a convergent route that is amenable to large scale preparation of the antibiotic in optically pure form. Natural source of azatyrosine; Therapeutic usage; Mechanism of synthesis. |
| Database: | Engineering Source |
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