Cutting-edge muscle recovery: using antifibrosis agents to improve healing.

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Bibliographic Details
Title: Cutting-edge muscle recovery: using antifibrosis agents to improve healing.
Authors: Li Y (AUTHOR), Fu FH (AUTHOR), Huard J (AUTHOR)
Source: Physician & Sportsmedicine. May2005, Vol. 33 Issue 5, p44-50. 7p.
Abstract: IN BRIEF: Muscle injuries, the most frequent type of sports-related injury, present challenging problems in traumatology and sports medicine. Injured skeletal muscle can repair itself via spontaneous regeneration, but extracellular matrix overgrowth and collagen deposition can lead to fibrosis, resulting in incomplete functional recovery and a propensity for injury recurrence. Physicians may be able to improve skeletal muscle healing after injury when researchers understand more about the mechanisms involved in scar-tissue development. Techniques maybe refined to prevent muscle fibrosis--specifically via the inactivation of transforming growth factor-beta1--and, ultimately, improve muscle healing after injuries. [ABSTRACT FROM AUTHOR]
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Database: Education Research Complete
Description
Abstract:IN BRIEF: Muscle injuries, the most frequent type of sports-related injury, present challenging problems in traumatology and sports medicine. Injured skeletal muscle can repair itself via spontaneous regeneration, but extracellular matrix overgrowth and collagen deposition can lead to fibrosis, resulting in incomplete functional recovery and a propensity for injury recurrence. Physicians may be able to improve skeletal muscle healing after injury when researchers understand more about the mechanisms involved in scar-tissue development. Techniques maybe refined to prevent muscle fibrosis--specifically via the inactivation of transforming growth factor-beta1--and, ultimately, improve muscle healing after injuries. [ABSTRACT FROM AUTHOR]
ISSN:00913847