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Cutting-edge muscle recovery: using antifibrosis agents to improve healing.

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Title: Cutting-edge muscle recovery: using antifibrosis agents to improve healing.
Authors: Li Y (AUTHOR), Fu FH (AUTHOR), Huard J (AUTHOR)
Source: Physician & Sportsmedicine. May2005, Vol. 33 Issue 5, p44-50. 7p.
Abstract: IN BRIEF: Muscle injuries, the most frequent type of sports-related injury, present challenging problems in traumatology and sports medicine. Injured skeletal muscle can repair itself via spontaneous regeneration, but extracellular matrix overgrowth and collagen deposition can lead to fibrosis, resulting in incomplete functional recovery and a propensity for injury recurrence. Physicians may be able to improve skeletal muscle healing after injury when researchers understand more about the mechanisms involved in scar-tissue development. Techniques maybe refined to prevent muscle fibrosis--specifically via the inactivation of transforming growth factor-beta1--and, ultimately, improve muscle healing after injuries. [ABSTRACT FROM AUTHOR]
Copyright of Physician & Sportsmedicine is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Education Research Complete
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DbLabel: Education Research Complete
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Cutting-edge muscle recovery: using antifibrosis agents to improve healing.
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  Data: <searchLink fieldCode="AR" term="%22Li+Y%22">Li Y</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fu+FH%22">Fu FH</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Huard+J%22">Huard J</searchLink> (AUTHOR)
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  Label: Abstract
  Group: Ab
  Data: IN BRIEF: Muscle injuries, the most frequent type of sports-related injury, present challenging problems in traumatology and sports medicine. Injured skeletal muscle can repair itself via spontaneous regeneration, but extracellular matrix overgrowth and collagen deposition can lead to fibrosis, resulting in incomplete functional recovery and a propensity for injury recurrence. Physicians may be able to improve skeletal muscle healing after injury when researchers understand more about the mechanisms involved in scar-tissue development. Techniques maybe refined to prevent muscle fibrosis--specifically via the inactivation of transforming growth factor-beta1--and, ultimately, improve muscle healing after injuries. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Physician & Sportsmedicine is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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