Darunavir is predominantly unbound to protein in cerebrospinal fluid and concentrations exceed the wild-type HIV-1 median 90% inhibitory concentration.
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| Title: | Darunavir is predominantly unbound to protein in cerebrospinal fluid and concentrations exceed the wild-type HIV-1 median 90% inhibitory concentration. |
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| Authors: | Croteau D (AUTHOR), Rossi SS (AUTHOR), Best BM (AUTHOR), Capparelli E (AUTHOR), Ellis RJ (AUTHOR), Clifford DB (AUTHOR), Collier AC (AUTHOR), Gelman BB (AUTHOR), Marra CM (AUTHOR), McArthur J (AUTHOR), McCutchan JA (AUTHOR), Morgello S (AUTHOR), Simpson DM (AUTHOR), Grant I (AUTHOR), Letendre S (AUTHOR), CHARTER Group (CORPORATE AUTHOR), Croteau, David1 (AUTHOR), Rossi, Steven S (AUTHOR), Best, Brookie M (AUTHOR), Capparelli, Edmund (AUTHOR) |
| Source: | Journal of Antimicrobial Chemotherapy (JAC). Mar2013, Vol. 68 Issue 3, p684-689. 6p. |
| Database: | Environment Complete |
| ISSN: | 03057453 |
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| DOI: | 10.1093/jac/dks441 |