Pharmacokinetic analysis of nicotine and its metabolites (cotinine and trans-3′-hydroxycotinine) in male Sprague-Dawley rats following nose-only inhalation, oral gavage, and intravenous infusion of nicotine.
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| Title: | Pharmacokinetic analysis of nicotine and its metabolites (cotinine and trans-3′-hydroxycotinine) in male Sprague-Dawley rats following nose-only inhalation, oral gavage, and intravenous infusion of nicotine. |
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| Authors: | Tang, Yunan1 (AUTHOR) yunan.tang@fda.hhs.gov, Bryant, Matthew S1 (AUTHOR), Li, Miao1 (AUTHOR), Min, Seonggi1 (AUTHOR), Pellar, Gregory1 (AUTHOR), Wu, Qiangen1 (AUTHOR), Yang, Dong-Jin1 (AUTHOR), Kang, Hyun-Ki1 (AUTHOR), Sepehr, Estatira1 (AUTHOR), He, Xiaobo1 (AUTHOR), McLellen, Florence1 (AUTHOR), Lewis, Sherry M1 (AUTHOR), Greenhaw, James1 (AUTHOR), Fisher, Jeffrey1 (AUTHOR), Yang, Xiaoxia1 (AUTHOR), Chemerynski, Susan2 (AUTHOR), Yee, Steven B2 (AUTHOR), Rosenfeldt, Hans2 (AUTHOR), Yeager, R Philip2 (AUTHOR), Howard, Paul C1 (AUTHOR) |
| Source: | Toxicological Sciences. Dec2024, Vol. 202 Issue 2, p196-209. 14p. |
| Database: | Environment Complete |
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| ISSN: | 10966080 |
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| DOI: | 10.1093/toxsci/kfae120 |