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Metabolic activation and cytotoxicity of ibudilast mediated by CYP3A4.

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Title: Metabolic activation and cytotoxicity of ibudilast mediated by CYP3A4.
Authors: Dong, Lingwen1 (AUTHOR), Hao, Xialing1 (AUTHOR), Liu, Minglu1 (AUTHOR), Zhai, Yanjie1 (AUTHOR), Wang, Xu1 (AUTHOR), Tian, Xiaobao1 (AUTHOR), Li, Weiwei2 (AUTHOR) weiweili0615@163.com, Peng, Ying1 (AUTHOR) yingpeng1999@163.com, Zheng, Jiang1,2 (AUTHOR) zhengneu@yahoo.com
Source: Archives of Toxicology. May2025, Vol. 99 Issue 5, p2023-2038. 16p.
Database: Environment Complete
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ISSN:03405761
DOI:10.1007/s00204-025-03995-4