ABBV-712-induced cardiac pathology in rats is related to off-target-driven acute vasodilation, tachycardia, and increased cardiac contractility.
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| Title: | ABBV-712-induced cardiac pathology in rats is related to off-target-driven acute vasodilation, tachycardia, and increased cardiac contractility. |
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| Authors: | Kohnken, Rebecca1 (AUTHOR), Fossey, Stacey2 (AUTHOR), Buck, Wayne R2 (AUTHOR), Segreti, Jason1 (AUTHOR), Treadway, Jessica1 (AUTHOR), Green, Jonathon1 (AUTHOR), Koshman, Yevgeniya E2 (AUTHOR), Zafiratos, Mark1 (AUTHOR), Mittelstadt, Scott3 (AUTHOR), Blomme, Eric4 (AUTHOR), Foley, Charles M1 (AUTHOR) |
| Source: | Toxicological Sciences. May2025, Vol. 205 Issue 1, p233-244. 12p. |
| Database: | Environment Complete |
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| FullText | Links: – Type: pdflink Text: Availability: 1 |
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| Header | DbId: eih DbLabel: Environment Complete An: 185321532 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: ABBV-712-induced cardiac pathology in rats is related to off-target-driven acute vasodilation, tachycardia, and increased cardiac contractility. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Kohnken%2C+Rebecca%22">Kohnken, Rebecca</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fossey%2C+Stacey%22">Fossey, Stacey</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Buck%2C+Wayne+R%22">Buck, Wayne R</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Segreti%2C+Jason%22">Segreti, Jason</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Treadway%2C+Jessica%22">Treadway, Jessica</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Green%2C+Jonathon%22">Green, Jonathon</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Koshman%2C+Yevgeniya+E%22">Koshman, Yevgeniya E</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zafiratos%2C+Mark%22">Zafiratos, Mark</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mittelstadt%2C+Scott%22">Mittelstadt, Scott</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Blomme%2C+Eric%22">Blomme, Eric</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Foley%2C+Charles+M%22">Foley, Charles M</searchLink><relatesTo>1</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Toxicological+Sciences%22">Toxicological Sciences</searchLink>. May2025, Vol. 205 Issue 1, p233-244. 12p. |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=eih&AN=185321532 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1093/toxsci/kfaf021 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 12 StartPage: 233 Titles: – TitleFull: ABBV-712-induced cardiac pathology in rats is related to off-target-driven acute vasodilation, tachycardia, and increased cardiac contractility. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kohnken, Rebecca – PersonEntity: Name: NameFull: Fossey, Stacey – PersonEntity: Name: NameFull: Buck, Wayne R – PersonEntity: Name: NameFull: Segreti, Jason – PersonEntity: Name: NameFull: Treadway, Jessica – PersonEntity: Name: NameFull: Green, Jonathon – PersonEntity: Name: NameFull: Koshman, Yevgeniya E – PersonEntity: Name: NameFull: Zafiratos, Mark – PersonEntity: Name: NameFull: Mittelstadt, Scott – PersonEntity: Name: NameFull: Blomme, Eric – PersonEntity: Name: NameFull: Foley, Charles M IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 10966080 Numbering: – Type: volume Value: 205 – Type: issue Value: 1 Titles: – TitleFull: Toxicological Sciences Type: main |
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