The Gluten-Free/Casein-Free Diet: A Double-Blind Challenge Trial in Children with Autism
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| Title: | The Gluten-Free/Casein-Free Diet: A Double-Blind Challenge Trial in Children with Autism |
|---|---|
| Language: | English |
| Authors: | Hyman, Susan L., Stewart, Patricia A., Foley, Jennifer |
| Source: | Journal of Autism and Developmental Disorders. Jan 2016 46(1):205-220. |
| Availability: | Springer. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: service-ny@springer.com; Web site: http://www.springerlink.com |
| Peer Reviewed: | Y |
| Page Count: | 16 |
| Publication Date: | 2016 |
| Document Type: | Journal Articles Reports - Research |
| Descriptors: | Dietetics, Sample Size, Statistical Analysis, Statistical Significance, Behavior Problems, Autism, Symptoms (Individual Disorders), Physiology, Safety, Young Children, Toddlers, Control Groups, Food, Nutrition, Counseling, Correlation, Outcomes of Treatment |
| DOI: | 10.1007/s10803-015-2564-9 |
| ISSN: | 0162-3257 |
| Abstract: | To obtain information on the safety and efficacy of the gluten-free/casein-free (GFCF) diet, we placed 14 children with autism, age 3-5 years, on the diet for 4-6 weeks and then conducted a double-blind, placebo-controlled challenge study for 12 weeks while continuing the diet, with a 12-week follow-up. Dietary challenges were delivered via weekly snacks that contained gluten, casein, gluten and casein, or placebo. With nutritional counseling, the diet was safe and well-tolerated. However, dietary challenges did not have statistically significant effects on measures of physiologic functioning, behavior problems, or autism symptoms. Although these findings must be interpreted with caution because of the small sample size, the study does not provide evidence to support general use of the GFCF diet. |
| Abstractor: | As Provided |
| Number of References: | 53 |
| Entry Date: | 2016 |
| Accession Number: | EJ1086641 |
| Database: | ERIC |
| Abstract: | To obtain information on the safety and efficacy of the gluten-free/casein-free (GFCF) diet, we placed 14 children with autism, age 3-5 years, on the diet for 4-6 weeks and then conducted a double-blind, placebo-controlled challenge study for 12 weeks while continuing the diet, with a 12-week follow-up. Dietary challenges were delivered via weekly snacks that contained gluten, casein, gluten and casein, or placebo. With nutritional counseling, the diet was safe and well-tolerated. However, dietary challenges did not have statistically significant effects on measures of physiologic functioning, behavior problems, or autism symptoms. Although these findings must be interpreted with caution because of the small sample size, the study does not provide evidence to support general use of the GFCF diet. |
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| ISSN: | 0162-3257 |
| DOI: | 10.1007/s10803-015-2564-9 |
