An Interdisciplinary Course on Computer-Aided Drug Discovery to Broaden Student Participation in Original Scientific Research
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| Title: | An Interdisciplinary Course on Computer-Aided Drug Discovery to Broaden Student Participation in Original Scientific Research |
|---|---|
| Language: | English |
| Authors: | Christopher Stratton, Avery Christensen, Chelsey Jordan, Brian A. Salvatore, Elahe Mahdavian (ORCID |
| Source: | Biochemistry and Molecular Biology Education. 2024 52(3):276-290. |
| Availability: | Wiley. Available from: John Wiley & Sons, Inc. 111 River Street, Hoboken, NJ 07030. Tel: 800-835-6770; e-mail: cs-journals@wiley.com; Web site: https://www.wiley.com/en-us |
| Peer Reviewed: | Y |
| Page Count: | 15 |
| Publication Date: | 2024 |
| Document Type: | Journal Articles Reports - Descriptive |
| Descriptors: | Educational Technology, Computer Assisted Instruction, Science Instruction, Drug Therapy, COVID-19, Pandemics, Active Learning, Student Research, Research Skills, Interdisciplinary Approach, Chemistry, Biology, Computer Science |
| Geographic Terms: | Louisiana |
| DOI: | 10.1002/bmb.21811 |
| ISSN: | 1470-8175 1539-3429 |
| Abstract: | We present a new highly interdisciplinary project-based course in computer aided drug discovery (CADD). This course was developed in response to a call for alternative pedagogical approaches during the COVID-19 pandemic, which caused the cancellation of a face-to-face summer research program sponsored by the Louisiana Biomedical Research Network (LBRN). The course integrates guided research and educational experiences for chemistry, biology, and computer science students. We implement research-based methods with publicly available tools in bioinformatics and molecular modeling to identify and prioritize promising antiviral drug candidates for COVID-19. The purpose of this course is three-fold: I. Implement an active learning and inclusive pedagogy that fosters student engagement and research mindset; II. Develop student interdisciplinary research skills that are highly beneficial in a broader scientific context; III. Demonstrate that pedagogical shifts (initially incurred during the COVID-19 pandemic) can furnish longer-term instructional benefits. The course, which has now been successfully taught a total of five times, incorporates four modules, including lectures/discussions, live demos, inquiry-based assignments, and science communication. |
| Abstractor: | As Provided |
| Entry Date: | 2024 |
| Accession Number: | EJ1425258 |
| Database: | ERIC |
| Abstract: | We present a new highly interdisciplinary project-based course in computer aided drug discovery (CADD). This course was developed in response to a call for alternative pedagogical approaches during the COVID-19 pandemic, which caused the cancellation of a face-to-face summer research program sponsored by the Louisiana Biomedical Research Network (LBRN). The course integrates guided research and educational experiences for chemistry, biology, and computer science students. We implement research-based methods with publicly available tools in bioinformatics and molecular modeling to identify and prioritize promising antiviral drug candidates for COVID-19. The purpose of this course is three-fold: I. Implement an active learning and inclusive pedagogy that fosters student engagement and research mindset; II. Develop student interdisciplinary research skills that are highly beneficial in a broader scientific context; III. Demonstrate that pedagogical shifts (initially incurred during the COVID-19 pandemic) can furnish longer-term instructional benefits. The course, which has now been successfully taught a total of five times, incorporates four modules, including lectures/discussions, live demos, inquiry-based assignments, and science communication. |
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| ISSN: | 1470-8175 1539-3429 |
| DOI: | 10.1002/bmb.21811 |
