Semiparametric Structural Equation Models with Interval-Censored Data

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Bibliographic Details
Title: Semiparametric Structural Equation Models with Interval-Censored Data
Language: English
Authors: Hongxi Li, Shuwei Li, Liuquan Sun, Xinyuan Song (ORCID 0000-0002-4877-3200)
Source: Structural Equation Modeling: A Multidisciplinary Journal. 2025 32(1):14-25.
Availability: Routledge. Available from: Taylor & Francis, Ltd. 530 Walnut Street Suite 850, Philadelphia, PA 19106. Tel: 800-354-1420; Tel: 215-625-8900; Fax: 215-207-0050; Web site: http://www.tandf.co.uk/journals
Peer Reviewed: Y
Page Count: 12
Publication Date: 2025
Document Type: Journal Articles
Reports - Research
Descriptors: Statistical Analysis, Statistical Studies, Structural Equation Models, Intervals, Censorship, Data, Nonparametric Statistics, Maximum Likelihood Statistics, Algorithms, Simulation, Alzheimers Disease, Computation, Mathematical Formulas
DOI: 10.1080/10705511.2024.2368023
ISSN: 1070-5511
1532-8007
Abstract: Structural equation models offer a valuable tool for delineating the complicated interrelationships among multiple variables, including observed and latent variables. Over the last few decades, structural equation models have successfully analyzed complete and right-censored survival data, exemplified by wide applications in psychological, social, or genomic studies. However, the existing methodology for structural equation modeling is not concerned with interval-censored data, a type of coarse survival data arising typically from periodic examinations for the occurrence of asymptomatic disease. The present study aims to fill this gap and provide a flexible semiparametric structural equation modeling framework. A general class of factor-augmented transformation models is proposed to model the interval-censored outcome of interest in the presence of latent risk factors. An expectation-maximization algorithm is subtly designed to conduct the nonparametric maximum likelihood estimation. Furthermore, the asymptotic properties of the proposed estimators are established by leveraging the empirical process theory. The numerical results obtained from extensive simulations and an application to the Alzheimer's disease data set demonstrate the proposed method's empirical performance and practical utility.
Abstractor: As Provided
Entry Date: 2025
Accession Number: EJ1457160
Database: ERIC
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Abstract:Structural equation models offer a valuable tool for delineating the complicated interrelationships among multiple variables, including observed and latent variables. Over the last few decades, structural equation models have successfully analyzed complete and right-censored survival data, exemplified by wide applications in psychological, social, or genomic studies. However, the existing methodology for structural equation modeling is not concerned with interval-censored data, a type of coarse survival data arising typically from periodic examinations for the occurrence of asymptomatic disease. The present study aims to fill this gap and provide a flexible semiparametric structural equation modeling framework. A general class of factor-augmented transformation models is proposed to model the interval-censored outcome of interest in the presence of latent risk factors. An expectation-maximization algorithm is subtly designed to conduct the nonparametric maximum likelihood estimation. Furthermore, the asymptotic properties of the proposed estimators are established by leveraging the empirical process theory. The numerical results obtained from extensive simulations and an application to the Alzheimer's disease data set demonstrate the proposed method's empirical performance and practical utility.
ISSN:1070-5511
1532-8007
DOI:10.1080/10705511.2024.2368023