Randomised Controlled Trial of Gaze-Based Attention Training Intervention for Infants with a Family History of Attention Deficit Hyperactivity Disorder: Follow-Up Outcomes at 2 and 3 Years

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Bibliographic Details
Title: Randomised Controlled Trial of Gaze-Based Attention Training Intervention for Infants with a Family History of Attention Deficit Hyperactivity Disorder: Follow-Up Outcomes at 2 and 3 Years
Language: English
Authors: Amy Goodwin, Emily J. H. Jones, Tony Charman (ORCID 0000-0003-1993-6549), Jannath Begum-Ali, Greg Pasco, Luke Mason, Rebecca Holman, Simona Salomone, Alexandra Hendry, Tessel Bazelmans, Tim J. Smith, Edmund J. S. Sonuga-Barke, Patrick Bolton, Sam Wass, Andrew Pickles, Mark H. Johnson, INTERSTAARS Team
Source: Journal of Attention Disorders. 2026 30(7):901-915.
Availability: SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: https://sagepub.com
Peer Reviewed: Y
Page Count: 15
Publication Date: 2026
Document Type: Journal Articles
Reports - Research
Descriptors: Eye Movements, Infants, Training, Intervention, Attention Deficit Hyperactivity Disorder, Toddlers, Program Effectiveness, Outcomes of Treatment, Inhibition, Self Control, Attention Control, Foreign Countries, Child Behavior
Geographic Terms: United Kingdom (London), United Kingdom (England)
Assessment and Survey Identifiers: Child Behavior Checklist
DOI: 10.1177/10870547261428660
ISSN: 1087-0547
1557-1246
Abstract: Objective: A previous randomised controlled trial of a computerised gaze-contingent attention training for 9-to-16-month infants with a family history of ADHD (intervention, n=20; control, n=23) found no endpoint differences on the primary outcome (an eye-tracking composite score of infant attention) nor on secondary outcomes (parent and observer ratings of infant attention in naturalistic contexts).Method: Here, we report follow-up at age 2 and 3 years to examine whether there are longer-term effects of the training. The pre-specified primary outcome was parent-reported early ADHD traits. Secondary outcomes included parent-report of inhibitory control and attention; researcher-rated observational measures of attentiveness, activity level and inhibition; and eye-tracking measures of cognitive control, attention disengagement and sustained attention. Results: At follow-up there was no intervention effect on the primary outcome parent-rated ADHD behaviours (effect size [ES] -0.28, 95% CIs -0.95 to 0.39). Secondary parent- and researcher-rated child behaviour and eye-tracking attention outcomes also did not significantly differ between the groups. The largest positive, albeit non-significant, effects were for the secondary outcomes parent-rated inhibitory control (ES=0.42 (95% CIs -0.09 to 0.94) and the composite eye-tracking measure (ES=0.40 (95% CIs -0.15 to 0.95). Conclusions: We demonstrate the feasibility of conducting experimental trials targeting early emerging ADHD characteristics in infancy. The intervention did not lead to significant differences in parent- or researcher-rated early ADHD behaviours or eye-tracking measures of attention control. However, the trend for long-term effects on CBQ inhibition, the attention composite and sustained attention justifies further interest. Further development and modification of the attention training may be necessary to test whether the approach holds promise as a potential pre-emptive intervention for infants with an elevated likelihood of ADHD. (J. of Att. Dis. 2026; 30(7) 901-915).
Abstractor: As Provided
Entry Date: 2026
Accession Number: EJ1507681
Database: ERIC
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Abstract:Objective: A previous randomised controlled trial of a computerised gaze-contingent attention training for 9-to-16-month infants with a family history of ADHD (intervention, n=20; control, n=23) found no endpoint differences on the primary outcome (an eye-tracking composite score of infant attention) nor on secondary outcomes (parent and observer ratings of infant attention in naturalistic contexts).Method: Here, we report follow-up at age 2 and 3 years to examine whether there are longer-term effects of the training. The pre-specified primary outcome was parent-reported early ADHD traits. Secondary outcomes included parent-report of inhibitory control and attention; researcher-rated observational measures of attentiveness, activity level and inhibition; and eye-tracking measures of cognitive control, attention disengagement and sustained attention. Results: At follow-up there was no intervention effect on the primary outcome parent-rated ADHD behaviours (effect size [ES] -0.28, 95% CIs -0.95 to 0.39). Secondary parent- and researcher-rated child behaviour and eye-tracking attention outcomes also did not significantly differ between the groups. The largest positive, albeit non-significant, effects were for the secondary outcomes parent-rated inhibitory control (ES=0.42 (95% CIs -0.09 to 0.94) and the composite eye-tracking measure (ES=0.40 (95% CIs -0.15 to 0.95). Conclusions: We demonstrate the feasibility of conducting experimental trials targeting early emerging ADHD characteristics in infancy. The intervention did not lead to significant differences in parent- or researcher-rated early ADHD behaviours or eye-tracking measures of attention control. However, the trend for long-term effects on CBQ inhibition, the attention composite and sustained attention justifies further interest. Further development and modification of the attention training may be necessary to test whether the approach holds promise as a potential pre-emptive intervention for infants with an elevated likelihood of ADHD. (J. of Att. Dis. 2026; 30(7) 901-915).
ISSN:1087-0547
1557-1246
DOI:10.1177/10870547261428660