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Cancer Patients with Major Depressive Disorder: Testing a Biobehavioral/Cognitive Behavior Intervention

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Title: Cancer Patients with Major Depressive Disorder: Testing a Biobehavioral/Cognitive Behavior Intervention
Language: English
Authors: Brothers, Brittany M., Yang, Hae-Chung, Strunk, Daniel R., Andersen, Barbara L.
Source: Journal of Consulting and Clinical Psychology. Apr 2011 79(2):253-260.
Availability: American Psychological Association. Journals Department, 750 First Street NE, Washington, DC 20002-4242. Tel: 800-374-2721; Tel: 202-336-5510; Fax: 202-336-5502; e-mail: order@apa.org; Web site: http://www.apa.org/publications
Peer Reviewed: Y
Page Count: 8
Publication Date: 2011
Document Type: Journal Articles
Reports - Research
Descriptors: Anxiety, Fatigue (Biology), Intervention, Quality of Life, Cancer, Rating Scales, Patients, Therapy, Depression (Psychology), Cognitive Restructuring, Behavior Modification, Biology, Program Evaluation, Coping, Counseling Techniques, Outcomes of Treatment, Counseling Effectiveness, Pretests Posttests, Symptoms (Individual Disorders), Mental Health, Pain
Assessment and Survey Identifiers: Hamilton Rating Scale for Depression, Beck Depression Inventory
DOI: 10.1037/a0022566
ISSN: 0022-006X
Abstract: Objective: In this Phase II trial, we evaluated a novel psychological treatment for depressed patients coping with the stresses of cancer. Effectiveness of a combined biobehavioral intervention (BBI) and cognitive behavior therapy (CBT) was studied. Method: Participants were 36 cancer survivors (mean age = 49 years; 88% Caucasian; 92% female) diagnosed with major depressive disorder. A single group pre-post design was used. Treatment consisted of up to 20 individual 75-min combined BBI/CBT sessions. Outcomes were change in interviewer (Hamilton Rating Scale for Depression; Williams, 1988) and self-rated depressive symptoms (Beck Depression Inventory-Second Edition; Beck, Steer, & Brown, 1996) as well as change in cancer relevant symptoms (Fatigue Symptom Inventory [Hann et al., 1998] and Brief Pain Questionnaire [Daut, Cleeland, & Flanery, 1983]) and quality of life (Medical Outcomes Study Short Form-36; Ware et al., 1995). Mixed-effects modeling, a reliability change index, and generalized linear models were used. All analyses were intent-to-treat. Results: Depressive symptoms significantly improved. In addition, 19 of 21 study completers met criteria for remission. Significant improvements were also noted in fatigue and mental health quality of life. Both concurrent anxiety disorders and high levels of cancer stress (Impact of Events Scale; Horowitz, Wilner, & Alvarez, 1979) were each associated with beginning and concluding treatment with greater depressive symptoms. Conclusions: CBT components were successfully incorporated into a previously efficacious intervention for reducing cancer stress. The BBI/CBT intervention warrants further research in evaluating its efficacy compared with well-established treatments for depression. (Contains 2 figures and 4 tables.)
Abstractor: As Provided
Number of References: 35
Entry Date: 2011
Accession Number: EJ933772
Database: ERIC
FullText Text:
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  Data: Cancer Patients with Major Depressive Disorder: Testing a Biobehavioral/Cognitive Behavior Intervention
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  Data: <searchLink fieldCode="AR" term="%22Brothers%2C+Brittany+M%2E%22">Brothers, Brittany M.</searchLink><br /><searchLink fieldCode="AR" term="%22Yang%2C+Hae-Chung%22">Yang, Hae-Chung</searchLink><br /><searchLink fieldCode="AR" term="%22Strunk%2C+Daniel+R%2E%22">Strunk, Daniel R.</searchLink><br /><searchLink fieldCode="AR" term="%22Andersen%2C+Barbara+L%2E%22">Andersen, Barbara L.</searchLink>
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  Data: <searchLink fieldCode="SO" term="%22Journal+of+Consulting+and+Clinical+Psychology%22"><i>Journal of Consulting and Clinical Psychology</i></searchLink>. Apr 2011 79(2):253-260.
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  Data: American Psychological Association. Journals Department, 750 First Street NE, Washington, DC 20002-4242. Tel: 800-374-2721; Tel: 202-336-5510; Fax: 202-336-5502; e-mail: order@apa.org; Web site: http://www.apa.org/publications
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  Data: <searchLink fieldCode="DE" term="%22Anxiety%22">Anxiety</searchLink><br /><searchLink fieldCode="DE" term="%22Fatigue+%28Biology%29%22">Fatigue (Biology)</searchLink><br /><searchLink fieldCode="DE" term="%22Intervention%22">Intervention</searchLink><br /><searchLink fieldCode="DE" term="%22Quality+of+Life%22">Quality of Life</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer%22">Cancer</searchLink><br /><searchLink fieldCode="DE" term="%22Rating+Scales%22">Rating Scales</searchLink><br /><searchLink fieldCode="DE" term="%22Patients%22">Patients</searchLink><br /><searchLink fieldCode="DE" term="%22Therapy%22">Therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Depression+%28Psychology%29%22">Depression (Psychology)</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+Restructuring%22">Cognitive Restructuring</searchLink><br /><searchLink fieldCode="DE" term="%22Behavior+Modification%22">Behavior Modification</searchLink><br /><searchLink fieldCode="DE" term="%22Biology%22">Biology</searchLink><br /><searchLink fieldCode="DE" term="%22Program+Evaluation%22">Program Evaluation</searchLink><br /><searchLink fieldCode="DE" term="%22Coping%22">Coping</searchLink><br /><searchLink fieldCode="DE" term="%22Counseling+Techniques%22">Counseling Techniques</searchLink><br /><searchLink fieldCode="DE" term="%22Outcomes+of+Treatment%22">Outcomes of Treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Counseling+Effectiveness%22">Counseling Effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Pretests+Posttests%22">Pretests Posttests</searchLink><br /><searchLink fieldCode="DE" term="%22Symptoms+%28Individual+Disorders%29%22">Symptoms (Individual Disorders)</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+Health%22">Mental Health</searchLink><br /><searchLink fieldCode="DE" term="%22Pain%22">Pain</searchLink>
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  Data: <searchLink fieldCode="SU" term="%22Hamilton+Rating+Scale+for+Depression%22">Hamilton Rating Scale for Depression</searchLink><br /><searchLink fieldCode="SU" term="%22Beck+Depression+Inventory%22">Beck Depression Inventory</searchLink>
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  Data: 10.1037/a0022566
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  Data: Objective: In this Phase II trial, we evaluated a novel psychological treatment for depressed patients coping with the stresses of cancer. Effectiveness of a combined biobehavioral intervention (BBI) and cognitive behavior therapy (CBT) was studied. Method: Participants were 36 cancer survivors (mean age = 49 years; 88% Caucasian; 92% female) diagnosed with major depressive disorder. A single group pre-post design was used. Treatment consisted of up to 20 individual 75-min combined BBI/CBT sessions. Outcomes were change in interviewer (Hamilton Rating Scale for Depression; Williams, 1988) and self-rated depressive symptoms (Beck Depression Inventory-Second Edition; Beck, Steer, & Brown, 1996) as well as change in cancer relevant symptoms (Fatigue Symptom Inventory [Hann et al., 1998] and Brief Pain Questionnaire [Daut, Cleeland, & Flanery, 1983]) and quality of life (Medical Outcomes Study Short Form-36; Ware et al., 1995). Mixed-effects modeling, a reliability change index, and generalized linear models were used. All analyses were intent-to-treat. Results: Depressive symptoms significantly improved. In addition, 19 of 21 study completers met criteria for remission. Significant improvements were also noted in fatigue and mental health quality of life. Both concurrent anxiety disorders and high levels of cancer stress (Impact of Events Scale; Horowitz, Wilner, & Alvarez, 1979) were each associated with beginning and concluding treatment with greater depressive symptoms. Conclusions: CBT components were successfully incorporated into a previously efficacious intervention for reducing cancer stress. The BBI/CBT intervention warrants further research in evaluating its efficacy compared with well-established treatments for depression. (Contains 2 figures and 4 tables.)
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      – Type: doi
        Value: 10.1037/a0022566
    Languages:
      – Text: English
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        PageCount: 8
        StartPage: 253
    Subjects:
      – SubjectFull: Anxiety
        Type: general
      – SubjectFull: Fatigue (Biology)
        Type: general
      – SubjectFull: Intervention
        Type: general
      – SubjectFull: Quality of Life
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      – SubjectFull: Cancer
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      – SubjectFull: Rating Scales
        Type: general
      – SubjectFull: Patients
        Type: general
      – SubjectFull: Therapy
        Type: general
      – SubjectFull: Depression (Psychology)
        Type: general
      – SubjectFull: Cognitive Restructuring
        Type: general
      – SubjectFull: Behavior Modification
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      – SubjectFull: Biology
        Type: general
      – SubjectFull: Program Evaluation
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      – SubjectFull: Coping
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      – SubjectFull: Counseling Techniques
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      – SubjectFull: Outcomes of Treatment
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      – SubjectFull: Pain
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      – SubjectFull: Hamilton Rating Scale for Depression
        Type: general
      – SubjectFull: Beck Depression Inventory
        Type: general
    Titles:
      – TitleFull: Cancer Patients with Major Depressive Disorder: Testing a Biobehavioral/Cognitive Behavior Intervention
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            – TitleFull: Journal of Consulting and Clinical Psychology
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