Membrana externa de Helicobacter pylori y su papel en la adhesión al epitelio gástrico.
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| Title: | Membrana externa de Helicobacter pylori y su papel en la adhesión al epitelio gástrico. |
|---|---|
| Alternate Title: | Helicobacter pylori Outer Membrane and Adhesion to the Gastric Epithelium. |
| Authors: | BARRAGÁN VIDAL, CARLOS EDUARDO1, GUTIÉRREZ-ESCOBAR, ANDRÉS JULIÁN1, CASTIBLANCO ROBAYO, LIZETH PAOLA2 |
| Source: | Universitas Médica. dec2015, Vol. 56 Issue 1, p44-62. 19p. |
| Subjects: | HELICOBACTER pylori infections, MEMBRANE proteins, BACTERIAL adhesion, BACTERIAL adhesins, HELICOBACTER pylori, PORINS (Proteins), LIPOPOLYSACCHARIDE structure, PHYSIOLOGY |
| Abstract (English): | The infection caused by Helicobacter pylori is linked to developing gastritis, peptic ulcer and gastric cancer. Several physiopathological mechanisms have been elucidated about the adherence to the gastric epithelium by this pathogen, being the outer membrane proteins (OMPs) its principal research scope. Thus, interest in this protein family is not only because its role during colonization and development of clinical outcomes but also, the fact that some of them can be considered as a novel therapeutic target. This review describes the principal OMP families detailing its role during epithelial cell's colonization and highlights how studying the OMPs properties could contribute towards the development of strategies to control and eradicate this important infection. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | La infección por Helicobacter pylori se relaciona con gastritis, desarrollo de úlceras y cáncer gástrico. Se han dilucidado varios mecanismos fisiopatológicos respecto al proceso de adherencia de este patógeno a las células epiteliales gástricas, de las cuales las proteínas de membrana (PME) constituyen uno de los principales agentes de estudio. El interés por estas proteínas radica no solo en su papel en el proceso de colonización y consecuente desarrollo del proceso patológico, sino también en que algunas de ellas podrían ser consideradas potenciales blancos terapéuticos. En esta revisión se describen las principales PME y su rol en el proceso de adhesión al epitelio, ya que su estudio y caracterización permitirá proponer alternativas eficientes para el control y erradicación de esta infección, que es una de las principales causas asociadas al cáncer gástrico en Colombia y el mundo. [ABSTRACT FROM AUTHOR] |
| Copyright of Universitas Médica is the property of Pontificia Universidad Javeriana and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 102850149 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Membrana externa de Helicobacter pylori y su papel en la adhesión al epitelio gástrico. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Helicobacter pylori Outer Membrane and Adhesion to the Gastric Epithelium. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22BARRAGÁN+VIDAL%2C+CARLOS+EDUARDO%22">BARRAGÁN VIDAL, CARLOS EDUARDO</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22GUTIÉRREZ-ESCOBAR%2C+ANDRÉS+JULIÁN%22">GUTIÉRREZ-ESCOBAR, ANDRÉS JULIÁN</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22CASTIBLANCO+ROBAYO%2C+LIZETH+PAOLA%22">CASTIBLANCO ROBAYO, LIZETH PAOLA</searchLink><relatesTo>2</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Universitas+Médica%22">Universitas Médica</searchLink>. dec2015, Vol. 56 Issue 1, p44-62. 19p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22HELICOBACTER+pylori+infections%22">HELICOBACTER pylori infections</searchLink><br /><searchLink fieldCode="DE" term="%22MEMBRANE+proteins%22">MEMBRANE proteins</searchLink><br /><searchLink fieldCode="DE" term="%22BACTERIAL+adhesion%22">BACTERIAL adhesion</searchLink><br /><searchLink fieldCode="DE" term="%22BACTERIAL+adhesins%22">BACTERIAL adhesins</searchLink><br /><searchLink fieldCode="DE" term="%22HELICOBACTER+pylori%22">HELICOBACTER pylori</searchLink><br /><searchLink fieldCode="DE" term="%22PORINS+%28Proteins%29%22">PORINS (Proteins)</searchLink><br /><searchLink fieldCode="DE" term="%22LIPOPOLYSACCHARIDE+structure%22">LIPOPOLYSACCHARIDE structure</searchLink><br /><searchLink fieldCode="DE" term="%22PHYSIOLOGY%22">PHYSIOLOGY</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: The infection caused by Helicobacter pylori is linked to developing gastritis, peptic ulcer and gastric cancer. Several physiopathological mechanisms have been elucidated about the adherence to the gastric epithelium by this pathogen, being the outer membrane proteins (OMPs) its principal research scope. Thus, interest in this protein family is not only because its role during colonization and development of clinical outcomes but also, the fact that some of them can be considered as a novel therapeutic target. This review describes the principal OMP families detailing its role during epithelial cell's colonization and highlights how studying the OMPs properties could contribute towards the development of strategies to control and eradicate this important infection. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: La infección por Helicobacter pylori se relaciona con gastritis, desarrollo de úlceras y cáncer gástrico. Se han dilucidado varios mecanismos fisiopatológicos respecto al proceso de adherencia de este patógeno a las células epiteliales gástricas, de las cuales las proteínas de membrana (PME) constituyen uno de los principales agentes de estudio. El interés por estas proteínas radica no solo en su papel en el proceso de colonización y consecuente desarrollo del proceso patológico, sino también en que algunas de ellas podrían ser consideradas potenciales blancos terapéuticos. En esta revisión se describen las principales PME y su rol en el proceso de adhesión al epitelio, ya que su estudio y caracterización permitirá proponer alternativas eficientes para el control y erradicación de esta infección, que es una de las principales causas asociadas al cáncer gástrico en Colombia y el mundo. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Universitas Médica is the property of Pontificia Universidad Javeriana and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=102850149 |
| RecordInfo | BibRecord: BibEntity: Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 19 StartPage: 44 Subjects: – SubjectFull: HELICOBACTER pylori infections Type: general – SubjectFull: MEMBRANE proteins Type: general – SubjectFull: BACTERIAL adhesion Type: general – SubjectFull: BACTERIAL adhesins Type: general – SubjectFull: HELICOBACTER pylori Type: general – SubjectFull: PORINS (Proteins) Type: general – SubjectFull: LIPOPOLYSACCHARIDE structure Type: general – SubjectFull: PHYSIOLOGY Type: general Titles: – TitleFull: Membrana externa de Helicobacter pylori y su papel en la adhesión al epitelio gástrico. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: BARRAGÁN VIDAL, CARLOS EDUARDO – PersonEntity: Name: NameFull: GUTIÉRREZ-ESCOBAR, ANDRÉS JULIÁN – PersonEntity: Name: NameFull: CASTIBLANCO ROBAYO, LIZETH PAOLA IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: dec2015 Type: published Y: 2015 Identifiers: – Type: issn-print Value: 00419095 Numbering: – Type: volume Value: 56 – Type: issue Value: 1 Titles: – TitleFull: Universitas Médica Type: main |
| ResultId | 1 |
