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Factores de riesgo para la infección por el virus de la hepatitis C en la Costa Caribe colombiana: un estudio de casos y controles.

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Title: Factores de riesgo para la infección por el virus de la hepatitis C en la Costa Caribe colombiana: un estudio de casos y controles.
Alternate Title: Risk factors by hepatitis C virus infection in Colombian Caribbean coast: a case control study.
Authors: de Jesús Yepes, Ismael1,2 ismayep@yahoo.com, Lince, Beatriz3, Caez, Clara4, de Vuono, Giovanni2
Source: Biomédica: Revista del Instituto Nacional de Salud. dic2016, Vol. 36 Issue 4, p1-23. 23p.
Abstract (English): Introduction: An estimated 6.8 - 8.9 million people are infected with hepatitis C virus in Latin America, of which less than 1% comes to receive antiviral treatment. Studies so far in Colombia, have attempted to determine the prevalence of the disease in some risk groups, thus preventing the identification of other factors potentially involved in the spread of infection. Objectives: To identify traditional and non-traditional risk factors for chronic hepatitis C in the Colombian Caribbean coast. Materials and methods: A case-control study (1: 3) matched by health care provider company and age (+/- 10 years) conducted in primary care level. All patients with a positive Elisa were performed confirmatory viral load. A multivariate logistic regression analysis identified independent predictors of infection. Results: Blood transfusion (OR 159.2, 95% CI 35.4 to 715; p <0.001) and history of hospitalization before 1994 (OR 4.7, 95% CI 1.3 to 17.1; p = 0.018) were identified as the only two independent predictors of infection. Conclusion: It is necessary to check the reproducibility of these results and performance cost-effectiveness studies before recommending its use in the design of new screening strategies. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Introducción. Se estima que aproximadamente 6,8-8,9 millones de personas están infectadas por el virus de la hepatitis C en Latinoamérica, de los cuales menos del 1% llega a recibir tratamiento antiviral. Los estudios realizados hasta ahora en Colombia han intentado determinar la prevalencia de la enfermedad en algunos grupos de riesgo, lo que ha impedido la identificación de otros factores potencialmente implicados en el contagio. Objetivos. Identificar factores de riesgo tradicionales y no tradicionales para hepatitis C crónica en la Costa Caribe colombiana. Materiales y métodos. Estudio de casos y controles (1:3) emparejados por empresa promotora de salud, edad (+/- 10 años), realizado en primer nivel de atención de la consulta de hepatología y gastroenterología. Todos los pacientes con Elisa positivo se realizaron una carga viral confirmatoria. Un análisis de regresión logística multivariante identificó los predictores independientes de infección. Resultados. La transfusión sanguínea (OR 159,2; IC 95% 35,4 - 715; p <0,001) y el antecedente de hospitalización antes de 1994 (OR 4,7; IC 95% 1,3 - 17,1; p = 0,018) se identificaron como los dos únicos predictores independientes de infección. Conclusión. Es necesario comprobar la reproducibilidad de estos resultados y realizar estudios de costo-efectividad antes de recomendar su utilización en el diseño de nuevas estrategias de cribado. [ABSTRACT FROM AUTHOR]
Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
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  Data: Factores de riesgo para la infecci&#243;n por el virus de la hepatitis C en la Costa Caribe colombiana: un estudio de casos y controles.
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  Data: Risk factors by hepatitis C virus infection in Colombian Caribbean coast: a case control study.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22de+Jes&#250;s+Yepes%2C+Ismael%22&quot;&gt;de Jes&#250;s Yepes, Ismael&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt;&lt;i&gt; ismayep@yahoo.com&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lince%2C+Beatriz%22&quot;&gt;Lince, Beatriz&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Caez%2C+Clara%22&quot;&gt;Caez, Clara&lt;/searchLink&gt;&lt;relatesTo&gt;4&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22de+Vuono%2C+Giovanni%22&quot;&gt;de Vuono, Giovanni&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Biom&#233;dica%3A+Revista+del+Instituto+Nacional+de+Salud%22&quot;&gt;Biom&#233;dica: Revista del Instituto Nacional de Salud&lt;/searchLink&gt;. dic2016, Vol. 36 Issue 4, p1-23. 23p.
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Introduction: An estimated 6.8 - 8.9 million people are infected with hepatitis C virus in Latin America, of which less than 1% comes to receive antiviral treatment. Studies so far in Colombia, have attempted to determine the prevalence of the disease in some risk groups, thus preventing the identification of other factors potentially involved in the spread of infection. Objectives: To identify traditional and non-traditional risk factors for chronic hepatitis C in the Colombian Caribbean coast. Materials and methods: A case-control study (1: 3) matched by health care provider company and age (+/- 10 years) conducted in primary care level. All patients with a positive Elisa were performed confirmatory viral load. A multivariate logistic regression analysis identified independent predictors of infection. Results: Blood transfusion (OR 159.2, 95% CI 35.4 to 715; p &lt;0.001) and history of hospitalization before 1994 (OR 4.7, 95% CI 1.3 to 17.1; p = 0.018) were identified as the only two independent predictors of infection. Conclusion: It is necessary to check the reproducibility of these results and performance cost-effectiveness studies before recommending its use in the design of new screening strategies. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Introducci&#243;n. Se estima que aproximadamente 6,8-8,9 millones de personas est&#225;n infectadas por el virus de la hepatitis C en Latinoam&#233;rica, de los cuales menos del 1% llega a recibir tratamiento antiviral. Los estudios realizados hasta ahora en Colombia han intentado determinar la prevalencia de la enfermedad en algunos grupos de riesgo, lo que ha impedido la identificaci&#243;n de otros factores potencialmente implicados en el contagio. Objetivos. Identificar factores de riesgo tradicionales y no tradicionales para hepatitis C cr&#243;nica en la Costa Caribe colombiana. Materiales y m&#233;todos. Estudio de casos y controles (1:3) emparejados por empresa promotora de salud, edad (+/- 10 a&#241;os), realizado en primer nivel de atenci&#243;n de la consulta de hepatolog&#237;a y gastroenterolog&#237;a. Todos los pacientes con Elisa positivo se realizaron una carga viral confirmatoria. Un an&#225;lisis de regresi&#243;n log&#237;stica multivariante identific&#243; los predictores independientes de infecci&#243;n. Resultados. La transfusi&#243;n sangu&#237;nea (OR 159,2; IC 95% 35,4 - 715; p &lt;0,001) y el antecedente de hospitalizaci&#243;n antes de 1994 (OR 4,7; IC 95% 1,3 - 17,1; p = 0,018) se identificaron como los dos &#250;nicos predictores independientes de infecci&#243;n. Conclusi&#243;n. Es necesario comprobar la reproducibilidad de estos resultados y realizar estudios de costo-efectividad antes de recomendar su utilizaci&#243;n en el dise&#241;o de nuevas estrategias de cribado. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Biom&#233;dica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Text: Spanish
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