CONCORDANCIA HISTOPATOLÓGICA ENTRE LA CITOLOGÍA Y LA BIOPSIA ANAL EN HOMBRES QUE TIENEN SEXO CON HOMBRES PORTADORES DE VIH Y NEOPLASIA INTRAEPITELIAL ANAL ASOCIADA A VPH.
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| Title: | CONCORDANCIA HISTOPATOLÓGICA ENTRE LA CITOLOGÍA Y LA BIOPSIA ANAL EN HOMBRES QUE TIENEN SEXO CON HOMBRES PORTADORES DE VIH Y NEOPLASIA INTRAEPITELIAL ANAL ASOCIADA A VPH. |
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| Alternate Title: | HISTOPATHOLOGICAL COMPARISON BETWEEN CYTOLOGY AND ANAL BIOPSY IN MEN WHO HAVE SEX WITH MEN WHO ARE HIV CARRIERS AND ANAL INTRAEPITHELIAL NEOPLASIA ASSOCIATED WITH HPV. CONCORDÂNCIA HISTOPATOLÓGICA ENTRE A CITOLOGIA E A BIÓPSIA ANAL EM HOMENS QUE FAZEM SEXO COM HOMENS PORTADORES DE HIV E NEOPLASIA INTRAEPITELIAL ASSOCIADAS COM HPV. |
| Authors: | Bajo Ríos, Christian1 bajo99@hotmail.com, Ramírez Cabezas, Francisco2, García Sobarzo, Ricardo3 |
| Source: | Revista Medicina. 2015, Vol. 19 Issue 1, p5-9. 5p. |
| Subjects: | HIV-positive men, PAPILLOMAVIRUS diseases, ANAL intraepithelial neoplasia, HEALTH |
| Abstract (English): | Objective: to determine the matching of the results of cytology and anal biopsy in men who have sex with men (MSM) who are HIV carriers and anal intraepithelial neoplasia (AIN) associated with human papillomavirus (HPV). Materials and methods: cross-sectional observational study from December 2011 to December 2013 to determine the matching of the results of cytology and anal biopsy in men who have sex with men (MSM) who are HIV carriers and AIN associated with HPV in patients with Infectious Diseases at the La Raza National Medical Center. Descriptive statistical analysis was performed. Results: 92 HIV positive and HPV positive subjects were studied, the final histopathological report of anal biopsies were: low-grade intraepithelial neoplasia in 39%, high-grade intraepithelial neoplasia 4%, atypical cells of undetermined significance 3%, normal in 27, with reactive inflammatory changes in 23% and inadequate samples for diagnosis 9%. The matching observed between both diagnostic methods was 0.90 based on Cronbach's alpha. Conclusion: the matching degree of 90% of the anal Pap smears and biopsies indicates that they are good monitoring methods of patients infected with HIV and HPV, and can detect precancerous lesions in a timely manner, providing prompt diagnosis and treatment. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Objetivo: determinar la concordancia de los resultados de la citología y la biopsia anal en hombres que tienen sexo con hombres (HSH) portadores de VIH y neoplasia intraepitelial anal (NIA) asociada a virus del papiloma humano (VPH). Materiales y métodos: estudio observacional transversal, de diciembre de 2011 a diciembre de 2013 para determinar la concordancia de los resultados de la citología y la biopsia anal en hombres que tienen sexo con hombres (HSH) portadores de VIH y NIA asociada a VPH en pacientes del hospital de Infectología del Centro Médico Nacional la Raza. Se realizó análisis estadísticos descriptivos. Resultados: se estudiaron 92 sujetos VIH positivos y VPH positivo, el reporte histopatológico definitivo de las biopsias anales fueron: neoplasia intraepitelial de bajo grado en 39 %, neoplasia intraepitelial de alto grado 4 %, células atípicas de significado incierto 3 %, normales en 27 %, con cambios infamatorios reactivos en 23 % y muestras inadecuadas para el diagnóstico el 9 %. La concordancia observada entre los dos métodos diagnósticos fue de 0.90 según alfa de Crobanch. Conclusión: el grado de concordancia del 90 % de las biopsias y citologías anales, indica que son buenos métodos de seguimiento de los pacientes infectados con VIH y VPH, y permite detectar en forma oportuna lesiones precancerígenas, brindando diagnóstico y tratamiento oportuno. [ABSTRACT FROM AUTHOR] |
| Abstract (Portuguese): | Objetivo: determinar a concordância dos resultados do exame citológico e a biópsia anal em homens que fazem sexo com homens (HSH) portadores de HIV e neoplasia intraepitelial anal (NIA) associada com o vírus do papiloma humano (HPV). Material e método: estudo observacional transversal, de dezembro de 2011 a dezembro de 2013 para determinar a concordância dos resultados do exame de citologia e a biópsia anal em homens que fazem sexo com homens (HSH) portadores de HIV e NIA associadas com HPV em pacientes do hospital de Infectologia do Centro Médico Nacional da Raça. A análise estatística descritiva foi realizada. Resultados: foram estudados 92 indivíduos HIV positivos e HPV positivos, o laudo histopatológico definitivo de biópsias anais foi: neoplasia intra-epitelial de baixo grau em 39 %, neoplasia intraepitelial de alto grau 4%, células atípicas de significado incerto 3%, normal em 27%, com alterações inflamatórias reativas em 23% e de amostragem inadequada para o diagnóstico em 9%. A concordância observada entre os dois métodos de diagnóstico foi de 0,90 segundo alfa de Crobanch. Conclusão: o grau de concordância nos 90% de biópsias e citologias anais indica que são todos bons métodos de seguimento dos pacientes infectados com HIV e HPV e permite detectar oportunamente lesões pré-cancerosas, fornecendo o diagnóstico e o tratamento oportuno. [ABSTRACT FROM AUTHOR] |
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| Database: | MedicLatina |
| Abstract: | Objective: to determine the matching of the results of cytology and anal biopsy in men who have sex with men (MSM) who are HIV carriers and anal intraepithelial neoplasia (AIN) associated with human papillomavirus (HPV). Materials and methods: cross-sectional observational study from December 2011 to December 2013 to determine the matching of the results of cytology and anal biopsy in men who have sex with men (MSM) who are HIV carriers and AIN associated with HPV in patients with Infectious Diseases at the La Raza National Medical Center. Descriptive statistical analysis was performed. Results: 92 HIV positive and HPV positive subjects were studied, the final histopathological report of anal biopsies were: low-grade intraepithelial neoplasia in 39%, high-grade intraepithelial neoplasia 4%, atypical cells of undetermined significance 3%, normal in 27, with reactive inflammatory changes in 23% and inadequate samples for diagnosis 9%. The matching observed between both diagnostic methods was 0.90 based on Cronbach's alpha. Conclusion: the matching degree of 90% of the anal Pap smears and biopsies indicates that they are good monitoring methods of patients infected with HIV and HPV, and can detect precancerous lesions in a timely manner, providing prompt diagnosis and treatment. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 13900218 |
| DOI: | 10.23878/medicina.v19i1.659 |
