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Nuevos enfoques moleculares en la regulación de la adipogénesis. El papel de la Conexina 43.

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Title: Nuevos enfoques moleculares en la regulación de la adipogénesis. El papel de la Conexina 43.
Alternate Title: New molecular approaches in adipogenesis regulation: The Connexin 43 Role.
Authors: Rojas-Gomez, Diana Marcela1, Angarita Davila, Lisse2, Cohen-Massabo, Maria Alejandra1, Giacometto, Marcela1, Rojas, Joselyn3,4, Wilches-Duran, Sandra5, Graterol-Rivas, Modesto4, Cerda, Marco5, Contreras-Velasquez, Julio5, Graterol-Silva, Rosemily5, Torres, Maritza3,6, Ortiz, Rina3,7, Siguencia, Wilson3,8, Gonzalez-Casanova, Jorge Enrique9 jorgoca2@gmail.com
Source: Archivos Venezolanos de Farmacología y Terapéutica. 2016, Vol. 35 Issue 4, p86-91. 6p.
Subjects: ADIPOGENESIS, CONNEXINS, ENERGY consumption, PHYSICAL activity, PATHOLOGICAL physiology
Abstract (English): The global prevalence of obesity has been increased rapidly over the past few years mainly due to changes in the lifestyle of the population with a significant increase in energy consumption and decreased levels of physical activity. As a result, the scientific community is interested in a deeper understanding of the mechanisms that regulate the pathophysiology of obesity. In this context, adipogenesis process is an important target of study to understand the obesity and associated pathologies. Recently has been emerged important evidence that involve gap junction channel protein connexin 43 (Cx43) in the regulation of processes related to adipogenesis, whose role is fundamentally anti-adipogenic. However, new functions of Cx43 in the regulation of adipose tissue function also continued to emerge. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): La prevalencia de la obesidad a nivel mundial se ha incrementado rápidamente durante los últimos años debido principalmente a los cambios en el estilo de vida de la población con un aumento significativo en el consumo de energía y disminución de los niveles de actividad física. Es por esto que la comunidad científica está interesada en comprender de forma más profunda los mecanismos que regulan la fisiopatología de la obesidad. Dentro de los diferentes blancos de estudio se encuentra la adipogénesis, cuyo entendimiento es fundamental para comprender el desarrollo de la obesidad y las patologías asociadas a esta. Recientemente ha surgido importantes evidencias que involucran a la proteína de canales de "Gap Junction" conexina 43 (Cx43) en la regulación de los procesos relacionados con adipogénesis, cuyo papel es básicamente anti-adipogénico, sin embargo, nuevas funciones de Cx43 en la regulación de la formación del tejido adiposo siguen descubriéndose. [ABSTRACT FROM AUTHOR]
Copyright of Archivos Venezolanos de Farmacología y Terapéutica is the property of Archivos Venezolanos de Farmacologia y Terapeutica and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
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PubType: Academic Journal
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  Data: Nuevos enfoques moleculares en la regulación de la adipogénesis. El papel de la Conexina 43.
– Name: TitleAlt
  Label: Alternate Title
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  Data: New molecular approaches in adipogenesis regulation: The Connexin 43 Role.
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  Data: <searchLink fieldCode="AR" term="%22Rojas-Gomez%2C+Diana+Marcela%22">Rojas-Gomez, Diana Marcela</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Angarita+Davila%2C+Lisse%22">Angarita Davila, Lisse</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Cohen-Massabo%2C+Maria+Alejandra%22">Cohen-Massabo, Maria Alejandra</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Giacometto%2C+Marcela%22">Giacometto, Marcela</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Rojas%2C+Joselyn%22">Rojas, Joselyn</searchLink><relatesTo>3,4</relatesTo><br /><searchLink fieldCode="AR" term="%22Wilches-Duran%2C+Sandra%22">Wilches-Duran, Sandra</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Graterol-Rivas%2C+Modesto%22">Graterol-Rivas, Modesto</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Cerda%2C+Marco%22">Cerda, Marco</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Contreras-Velasquez%2C+Julio%22">Contreras-Velasquez, Julio</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Graterol-Silva%2C+Rosemily%22">Graterol-Silva, Rosemily</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Torres%2C+Maritza%22">Torres, Maritza</searchLink><relatesTo>3,6</relatesTo><br /><searchLink fieldCode="AR" term="%22Ortiz%2C+Rina%22">Ortiz, Rina</searchLink><relatesTo>3,7</relatesTo><br /><searchLink fieldCode="AR" term="%22Siguencia%2C+Wilson%22">Siguencia, Wilson</searchLink><relatesTo>3,8</relatesTo><br /><searchLink fieldCode="AR" term="%22Gonzalez-Casanova%2C+Jorge+Enrique%22">Gonzalez-Casanova, Jorge Enrique</searchLink><relatesTo>9</relatesTo><i> jorgoca2@gmail.com</i>
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  Data: <searchLink fieldCode="JN" term="%22Archivos+Venezolanos+de+Farmacología+y+Terapéutica%22">Archivos Venezolanos de Farmacología y Terapéutica</searchLink>. 2016, Vol. 35 Issue 4, p86-91. 6p.
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  Data: <searchLink fieldCode="DE" term="%22ADIPOGENESIS%22">ADIPOGENESIS</searchLink><br /><searchLink fieldCode="DE" term="%22CONNEXINS%22">CONNEXINS</searchLink><br /><searchLink fieldCode="DE" term="%22ENERGY+consumption%22">ENERGY consumption</searchLink><br /><searchLink fieldCode="DE" term="%22PHYSICAL+activity%22">PHYSICAL activity</searchLink><br /><searchLink fieldCode="DE" term="%22PATHOLOGICAL+physiology%22">PATHOLOGICAL physiology</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: The global prevalence of obesity has been increased rapidly over the past few years mainly due to changes in the lifestyle of the population with a significant increase in energy consumption and decreased levels of physical activity. As a result, the scientific community is interested in a deeper understanding of the mechanisms that regulate the pathophysiology of obesity. In this context, adipogenesis process is an important target of study to understand the obesity and associated pathologies. Recently has been emerged important evidence that involve gap junction channel protein connexin 43 (Cx43) in the regulation of processes related to adipogenesis, whose role is fundamentally anti-adipogenic. However, new functions of Cx43 in the regulation of adipose tissue function also continued to emerge. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: La prevalencia de la obesidad a nivel mundial se ha incrementado rápidamente durante los últimos años debido principalmente a los cambios en el estilo de vida de la población con un aumento significativo en el consumo de energía y disminución de los niveles de actividad física. Es por esto que la comunidad científica está interesada en comprender de forma más profunda los mecanismos que regulan la fisiopatología de la obesidad. Dentro de los diferentes blancos de estudio se encuentra la adipogénesis, cuyo entendimiento es fundamental para comprender el desarrollo de la obesidad y las patologías asociadas a esta. Recientemente ha surgido importantes evidencias que involucran a la proteína de canales de "Gap Junction" conexina 43 (Cx43) en la regulación de los procesos relacionados con adipogénesis, cuyo papel es básicamente anti-adipogénico, sin embargo, nuevas funciones de Cx43 en la regulación de la formación del tejido adiposo siguen descubriéndose. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Archivos Venezolanos de Farmacología y Terapéutica is the property of Archivos Venezolanos de Farmacologia y Terapeutica and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=122902414
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      – SubjectFull: ADIPOGENESIS
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      – SubjectFull: ENERGY consumption
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