Evolución del descenso testicular en embriones y fetos humanos.

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Bibliographic Details
Title:	Evolución del descenso testicular en embriones y fetos humanos.
Alternate Title:	Testicular descent evolution in human embryos y fetus.
Authors:	Ortiz, M. S.¹ mauriciosebastianortiz2@gmail.com, Ortiz, M. A.¹, Guidobono, J. A.¹, Forlino, D.¹
Source:	Revista Argentina de Anatomia Online. 2016, Vol. 7 Issue 2, p57-63. 7p.
Abstract (English):	Introduction: The testicular descent has been an object of multiple studies that try to determine the morfo genetic causes that take it across the development, to its definitive escrotal place, having originated in the abdomen. The target of this work was to study the development of the Testicular Descent (TD) in embryos and human fetuses using 3 (three) methods, correlating the results of each of them. Material and methods: 4 human embryos of the 7th to the 12th week of development were studied through histological study of serialized sections. Also the dissection of abdomen and pelvis of eleven (11) fetuses of 14th to 28th weeks of intrauterine development had been done. Finally, 5 human fetuses stillbirths were evaluated by Magnetic Resonance Imaging (MRI) with a gestational age that goes from the 10th to the 23rd week of gestation. Results: In embryonic stages, the differential characters of the male gonads with the respective elements mesonefros linked to them have been observed; it has been also studied the inguinal ligament of the mesonefros linked particularly to the caudal end of the gonad and their relations with the abdominal wall to the scrotal area. The segments, that are ultimately the testis gubernaculm, are also checked. In the study of fetal material by dissection, we have observed that from the 22 testicles studied, only 5 (22.7%) are located on the LB, the remaininf 17 (77.3%) were below this repair. At 20 weeks of EG, they were below the LB but less than 10 mm of this, and from this age began to exceed this measure. The asymmetry of descent found in the 11 fetuses studied was 72.7% (8 cases), and only 27.3% of the studied specimens are symmetrical at the decline of both gonads. The studies using magnetic resonance imaging in fetuses set without dissect is found the location, the size and position of the gonads left and right showing in a very high percentage an asymmetry of height, and in all cases its strictly display position without abdominal fastening elements. Conclusion: For us there is no active mechanism in the testicular descent to the bags and as in any morphogenetic topic we observed differences in the gonadal location in specimens with comparable age and in the case of limited material up to the 7th month of development practically all the testicles studied were even, at different heights, in the abdomen. [ABSTRACT FROM AUTHOR]
Abstract (Spanish):	Introducción: El descenso testicular ha sido objeto de múltiples estudios que pretenden determinar los cambios morfológicos que lo llevan a través del desarrollo, a su ubicación definitiva escrotal habiéndose originado en el abdomen. El objetivo de este trabajo fue estudiar el desarrollo del Descenso Testicular (DT) en embriones y fetos humanos utilizando 3 (tres) métodos de observación diferente. Material y metodos: Se estudiaron 4 embriones humanos de la 7ª a la 12ª semana de desarrollo mediante estudio histológico de cortes seriados. Además se realizó la disección de abdomen y pelvis de once (11) fetos de 14ª a 28ª semanas del desarrollo intrauterino. Por último, se evaluaron 5 fetos humanos mortinatos mediante Resonancia Magnética (RM) con una edad gestacional que va desde la 10ª a la 23ª semana de gestación. Resultados: En etapas embrionaria se han objetivado, los caracteres diferenciales de las gónadas masculina con los respectivos elementos mesonéfricos vinculados a las mismas; se ha estudiado también el ligamento inguinal del mesonefros vinculado particularmente al extremo caudal de la gónada y sus relaciones con la pared abdominal hasta la zona escrotal. Asimismo se comprueban los segmentos que constituyen en definitiva el gubernaculm testis. En el estudio del material fetal mediante disección hemos, observado de que de los 22 testículos estudiados, solo 5 (22,7%) se encuentran sobre la LB, los 17 (77,3%) restantes se encontraban por debajo de este reparo. A las 20 semanas de EG se encontraban por debajo de la LB pero a menos de 10 mm de esta, y ya a partir de esta edad comenzaron a superar esta medida. La asimetría de descenso encontrada en los 11 fetos estudiados fue del 72,7% (8 casos), siendo solo el 27,3% de los especímenes estudiados simétricos el descenso de ambas gónadas. Los estudios realizados mediante resonancia magnética en fetos fijados sin disecar se constataron la ubicación, el tamaño y posición de las gónadas derecha e izquierda mostrando en un porcentaje muy alto asimetría de altura, y en todos los casos su posición estrictamente abdominal sin visualización de elementos de fijación. Conclusión: Para nosotros no existe un mecanismo activo en el descenso testicular hacia las bolsas y como en cualquier tema morfogenético hemos observados diferencias en la ubicación gonadal en especímenes con edad comparable y tratándose de material limitado hasta el 7° mes de desarrollo prácticamente la totalidad de los testículos estudiados se encontraban aun, a diferentes alturas, en el abdomen. [ABSTRACT FROM AUTHOR]
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Database:	MedicLatina

Description
Abstract:	Introduction: The testicular descent has been an object of multiple studies that try to determine the morfo genetic causes that take it across the development, to its definitive escrotal place, having originated in the abdomen. The target of this work was to study the development of the Testicular Descent (TD) in embryos and human fetuses using 3 (three) methods, correlating the results of each of them. Material and methods: 4 human embryos of the 7th to the 12th week of development were studied through histological study of serialized sections. Also the dissection of abdomen and pelvis of eleven (11) fetuses of 14th to 28th weeks of intrauterine development had been done. Finally, 5 human fetuses stillbirths were evaluated by Magnetic Resonance Imaging (MRI) with a gestational age that goes from the 10th to the 23rd week of gestation. Results: In embryonic stages, the differential characters of the male gonads with the respective elements mesonefros linked to them have been observed; it has been also studied the inguinal ligament of the mesonefros linked particularly to the caudal end of the gonad and their relations with the abdominal wall to the scrotal area. The segments, that are ultimately the testis gubernaculm, are also checked. In the study of fetal material by dissection, we have observed that from the 22 testicles studied, only 5 (22.7%) are located on the LB, the remaininf 17 (77.3%) were below this repair. At 20 weeks of EG, they were below the LB but less than 10 mm of this, and from this age began to exceed this measure. The asymmetry of descent found in the 11 fetuses studied was 72.7% (8 cases), and only 27.3% of the studied specimens are symmetrical at the decline of both gonads. The studies using magnetic resonance imaging in fetuses set without dissect is found the location, the size and position of the gonads left and right showing in a very high percentage an asymmetry of height, and in all cases its strictly display position without abdominal fastening elements. Conclusion: For us there is no active mechanism in the testicular descent to the bags and as in any morphogenetic topic we observed differences in the gonadal location in specimens with comparable age and in the case of limited material up to the 7th month of development practically all the testicles studied were even, at different heights, in the abdomen. [ABSTRACT FROM AUTHOR]
ISSN:	1853256X