Bibliographic Details
| Title: |
Complicaciones postoperatorias por descontrol lipídico perioperatorio. Revisión sistemática. |
| Alternate Title: |
Postoperative complications due to perioperative lipid decontrol. Systematic review. |
| Authors: |
Georgina Ramírez-Reyes, Liliana1, Carrillo-Torres, Orlando2 orlo_78@hotmail.com, Brito-Ramírez, Fabiola3 |
| Source: |
Revista Mexicana de Anestesiología. jan-mar2021, Vol. 44 Issue 1, p34-42. 9p. |
| Subjects: |
LIPID metabolism, METHODOLOGY, DYSLIPIDEMIA, RANDOMIZED controlled trials, MEDICAL research |
| Abstract (English): |
Introduction: The alteration in lipid metabolism has been involved in the pathogenesis of postoperative complications primarily by inducing inflammatory processes that may affect morbidity, in addition an increase in vulnerability/sensitivity for ischemia reperfusion has been observed involved apoptosis by stress mediated by the endoplasmic reticulum. During the anesthetic procedure, serum lipid levels can affect the pharmacokinetics of various anesthetic agents. Objective: To determine if there is scientific evidence to prove or refute the development of complications in post-operated patients who present with lipid decontrol in the preoperative period. Methodology: A review was made in the literature through the search engines PubMed, ScienceDirect, and BiomedCentral. Results: With the search criteria, 17 studies were reviewed (controlled clinical trials, case and control studies, cohorts and basic experimental studies). Conclusions: Although it is necessary to improve the methodology of several articles reviewed and increase the number of them, in most of them a relationship was found between dyslipidemia with postoperative alterations that affect an increase in morbidity or mortality. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
Introducción: La alteración en el metabolismo de los lípidos se ha involucrado en la patogénesis de complicaciones postoperatorias, primordialmente por inducir procesos inflamatorios que pueden afectar la morbilidad, además se ha observado un aumento en la vulnerabilidad/sensibilidad por isquemia reperfusión implicada por apoptosis por estrés mediado por el retículo endoplásmico. Durante el procedimiento anestésico los niveles séricos de lípidos pueden afectar la farmacocinética de varios agentes anestésicos. Objetivo: Determinar si existe evidencia científica que compruebe o refute el desarrollo de complicaciones en pacientes postoperados que cursan con descontrol lipídico en el período preoperatorio. Metodología: Se realizó una revisión en la literatura mediante los buscadores PUBMED, ScienceDirect y BioMed Central. Resultados: Con los criterios de búsqueda se revisaron 17 estudios (ensayos clínicos controlados, estudios de casos y controles, cohortes y estudios experimentales básicos). Conclusiones: Aunque es necesario mejorar la metodología de varios artículos revisados y aumentar la cantidad de los mismos, en la mayor parte de ellos se encontró relación entre dislipidemia con alteraciones postoperatorias que inciden en un aumento de morbilidad o mortalidad. [ABSTRACT FROM AUTHOR] |
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| Database: |
MedicLatina |
