Bibliographic Details
| Title: |
Liver cancer mortality in Mexico: trend analysis from 1998 to 2018. |
| Authors: |
Álvarez, Christian S.1, Espinosa-Tamez, Priscilla2,3, López-Ridaura, Ruy2, Lamadrid-Figueroa, Héctor2, Melchor-Ruan, Javier4, McGlynn, Katherine A.1, Lajous, Martín2,5 mlajous@insp.mx |
| Source: |
Salud Pública de México. Jan/Feb2022, Vol. 64 Issue 1, p14-25. 12p. |
| Subjects: |
LIVER cancer, CANCER-related mortality, TREND analysis, ETIOLOGY of cancer, COHORT analysis |
| Geographic Terms: |
MEXICO |
| Abstract (English): |
Objective. To examine overall, sex, and state-specific liver cancer mortality trends in Mexico. Materials and methods. Joinpoint regression was used to examine the trends in age-standardized mortality rates of liver cancer between 1998-2018. Estimated annual percent change with 95% confidence intervals (95%CI) were computed. Age-period-cohort models were used to assess the effects of age, calendar year, and birth cohort. Results. The state-specific mortality rates ranged from 3.34 (Aguascalientes) to 7.96 (Chiapas) per 100 000 person-years. Sex-specific rates were roughly equal, nationwide. Overall, we observed a statistically significant decrease in liver cancer mortality rates between 1998-2018 (annual percent change, -0.8%; 95%CI -1.0, -0.6). The overall age-period-cohort models suggest that birth cohort may be the most important factor driving the trends. Conclusions. While there was overall decline in liver cancer mortality, differences in rates by region were observed. The regional differences may inform future studies of liver cancer etiology across the country. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
Objetivo. Examinar la tendencia general, por sexo y estado, de mortalidad por cáncer hepático en México. Material y métodos. Se utilizó regresión joinpoint para examinar las tendencias en las tasas de mortalidad estandarizadas por edad de cáncer hepático (1998-2018). Se estimó el cambio porcentual anual con intervalos de confianza al 95% (IC95%). Se usaron modelos de edad-periodo-cohorte para evaluar el efecto de edad, año calendario y cohorte de nacimiento. Resultados. La mortalidad osciló entre 3.34 (Aguascalientes) y 7.96 (Chiapas) por 100 000 años-persona. La mortalidad por sexo fue relativamente similar a nivel nacional. La mortalidad general disminuyó entre 1998-2018 (cambio porcentual anual, -0.8%; IC95% -1.0, -0.6). La cohorte de nacimiento parece ser el factor más importante que afecta las tendencias. Conclusiones. A pesar de la disminución de mortalidad por cáncer hepático, se observó variación regional en las tasas. Estas diferencias podrían informar estudios futuros sobre la etiología de cáncer hepático en México. [ABSTRACT FROM AUTHOR] |
|
Copyright of Salud Pública de México is the property of Instituto Nacional de Salud Publica and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
MedicLatina |
