Bibliographic Details
| Title: |
Relación entre hierro y diabetes mellitus gestacional: una revisión narrativa. |
| Alternate Title: |
Relationship between iron and gestational diabetes mellitus: a narrative review. |
| Authors: |
Alejandra Márquez-Ibarra, Adriana1,2, Estela Mariscal-Ramírez, Blanca2, González-Ponce, Ana María3 amgonzalez@unpa.edu.mx, Valbuena-Gregorio, Edith4 |
| Source: |
Ginecología y Obstetricia de México. may2022, Vol. 90 Issue 5, p434-442. 9p. |
| Subjects: |
GESTATIONAL diabetes, PREGNANCY complications, FETAL development, INSULIN resistance, OXIDATIVE stress, IRON overload, IRON deficiency, PREGNANT women |
| Abstract (English): |
OBJECTIVE: To evaluate the scientific evidence about the relationship between iron and gestational diabetes mellitus. METHODOLOGY: Narrative review, based on the search for articles published from 2000 to 2021 in the PubMed, LILACS, BIREME, NICE, SIGN and CENETEC databases with the MeSH: Iron, iron and diabetes, Iron overland, Gestational Diabetes and Iron Overland and Gestational Diabetes. Those related to the topic of interest were selected. RESULTS: 119 articles were found and only 34 were considered adequate for the purpose of the review because they were directly related to iron metabolism, gestational diabetes and iron as a cause of gestational diabetes. Cross-sectional studies, cases and controls, cohorts, trials, reviews and meta-analyses were obtained. CONCLUSIONS: The relationship between iron and gestational diabetes mellitus is not properly established; however, it has been related to the oxidative capacity of iron through different mechanisms that accentuate insulin resistance. It is suggested that high iron concentrations could be a risk factor for gestational diabetes mellitus. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
OBJETIVO: Evaluar la evidencia científica acerca de la relación entre el hierro y la diabetes mellitus gestacional. METODOLOGÍA: Revisión narrativa, fundamentada en la búsqueda de artículos publicados de 2000 a 2021 en las bases de datos de PubMed, LILACS, BIREME, NICE, SIGN y CENETEC con los MeSH: Iron, iron and diabetes, Iron overland, Gestational Diabetes y Iron overland and Gestational Diabetes. Se seleccionaron los relacionados con el tema de interés. RESULTADOS: Se encontraron 119 artículos y solo 34 se consideraron adecuados para el objetivo de la revisión porque estaban directamente relacionados con el metabolismo del hierro, diabetes gestacional y el hierro como causa de diabetes gestacional. Se obtuvieron estudios transversales, casos y controles, cohortes, ensayos, revisiones y metanálisis. CONCLUSIONES: La relación entre hierro y diabetes mellitus gestacional no está debidamente establecida; sin embargo, se ha relacionado con la capacidad oxidativa del hierro por diferentes mecanismos que acentúan la resistencia a la insulina. Se sugiere que las concentraciones elevadas de hierro podrían ser un factor de riesgo de diabetes mellitus gestacional. [ABSTRACT FROM AUTHOR] |
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| Database: |
MedicLatina |
