Bibliographic Details
| Title: |
Helmintiasis intestinal, eosinofilia e inmunomodulación parasitaria. |
| Alternate Title: |
Intestinal helminthiasis, eosinophilia and parasitic Immunomodulation. |
| Authors: |
Anita M., Murillo-Zavala1 anita.murillo@unesum.ed.ec, Andreina, Molina-Solórzano2 molina-andreina7551@unesum.edu.ec, Dessired, Peñafiel-Álvarez2 penafiel-maybe6197@unesum.edu.ec |
| Source: |
Revista Kasmera. 2022, Vol. 50, p1-14. 14p. |
| Subjects: |
TROPICAL medicine, IMMUNOLOGIC diseases, DEVELOPING countries, VACCINE effectiveness, TH2 cells |
| Abstract (English): |
Intestinal helminthiasis are a public health problem in tropical countries, especially in underdeveloped countries and in poor populations. Infection with these parasites causes a hematological response characterized by an increase in the number of circulating eosinophils in peripheral blood and tissues, which is known as eosinophilia. In this work, a systematic review of the literature published in the last 25 years was carried out on the classification of eosinophilia, the intestinal helminths that produce it, what are the immunological mechanisms that occur in humans in the face of these parasitosis, as well as the immune system evasion mechanisms used mainly by adult forms of these parasites, allergic reactions associated with activation of the immune system, immunological diseases and poor responses to vaccines. Finally, the function of the eosinophil as an effector cell of Th2 immunity against intestinal helminths is reviewed. This revision is registered in PROSPERO under ID number 215594. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
Las helmintiasis intestinales son un problema de salud pública en los países tropicales, en especial en los subdesarrollados y en la población de escasos recursos. La infección con estos parásitos origina una respuesta hematológica caracterizada por el aumento de la cantidad de eosinófilos circulantes en sangre periférica y en los tejidos, que se conoce como eosinofilia. En este trabajo se realizó una revisión sistemática de la literatura publicada, en los últimos 25 años sobre la clasificación de la eosinofilia, los helmintos intestinales que la producen, cuáles son los mecanismos inmunológicos que ocurren en el ser humano ante estas parasitosis, así como los mecanismos de evasión del sistema inmunitario utilizados, principalmente, por las formas adultas de éstos parásitos, las reacciones alérgicas asociadas a la activación del sistema inmune, las enfermedades inmunológicas y la pobre respuestas a las vacunas. Por último, se revisa la función del eosinófilo como célula efectora de la inmunidad Th2 contra los helmintos intestinales. Esta revisión está registrada en PROSPERO bajo el número ID 215594. [ABSTRACT FROM AUTHOR] |
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| Database: |
MedicLatina |
