Triple terapia simultánea en el tratamiento de cicatrices queloides.

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Bibliographic Details
Title:	Triple terapia simultánea en el tratamiento de cicatrices queloides.
Alternate Title:	TRIPLE THERAPY FOR THE TREATMENT OF KELOID SCARS.
Authors:	Franco-Rúa, Catalina¹, Hugo García, Víctor², Matta, Lorena³, Díaz G., Claudia Juliana¹ claudia.diaz@correounivalle.edu.co
Source:	Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica. abr-jun2024, Vol. 32 Issue 2, p180-188. 9p.
Subjects:	TRIAMCINOLONE acetonide, STANDARD deviations, EAR, TERTIARY care, COLD therapy, KELOIDS
Abstract (English):	Introduction: The purpose of the study was to describe the experience of treating keloid scars with simultaneous triple therapy (resection, cryotherapy, and intralesional triamcinolone acetonide) in patients treated at a tertiary care institution in Cali, Colombia. Methods: We conducted a descriptive, observational, retrospective study including patients diagnosed with keloid scars who received simultaneous triple therapy between 2017 and 2019. Patients who did not attend follow-up were excluded. Results: A total of 27 patients (17 women) were studied. The average age was 30.8 years (standard deviation: 11.7). The median duration of the keloid scar was 18 years. Phototype V was the most affected (33.3%), and the auricle was the main location (88.9%). Trauma was the most common cause of the scars. Previous treatment with intralesional corticosteroid infiltration was received by 33.3% (9 patients). 63% of patients presented with a single lesion. One lesion per patient was followed up for 6 months, with 66.7% (18 patients) showing no recurrence after treatment. Pain was the most significant adverse effect reported. Conclusions: Simultaneous triple therapy for keloid scar management in our study resulted in a 66.7% non-recurrence rate with minimal complications. This is the first study in Colombia on this treatment for keloid scars. [ABSTRACT FROM AUTHOR]
Abstract (Spanish):	Introducción: el propósito del estudio fue describir la experiencia de tratamiento de cicatrices queloides (CQ) con triple terapia simultánea (resección, crioterapia e infiltración con acetónido de triamcinolona intralesional) en un grupo de pacientes atendidos en una institución de tercer nivel en Cali, Colombia. Métodos: se realizó un estudio descriptivo, observacional y retrospectivo, y se incluyeron pacientes con diagnóstico de cicatrices queloides que recibieron tratamiento con triple terapia simultánea durante el período de 2017 a 2019; se excluyeron los pacientes que no asistieron al seguimiento. Resultados: se estudiaron 27 pacientes (17 mujeres); el promedio de edad fue de 30,8 años (desviación estándar de 11,7); la mediana de aparición de la cicatriz queloide fue de 18 años; el fototipo V fue el más afectado (33,3%); el pabellón auricular fue la principal localización (88,9%) y el trauma fue la causa de cicatriz más relevante; el 33,3% (9 pacientes) recibieron tratamiento previo con infiltración de corticosteroide intralesional. El 63% presentó solo una lesión. Se resalta que se realizó seguimiento durante seis meses a una lesión por paciente, de las cuales, el 66,7% (18) no recurrieron posterior al manejo. Se encontró el dolor como efecto adverso más relevante. Conclusiones: la triple terapia simultánea para el manejo de las CQ en nuestro estudio mostró una respuesta sin recidiva en el 66,7% de los casos, con complicaciones mínimas. Este representa el primer estudio en Colombia en pacientes con CQ. [ABSTRACT FROM AUTHOR]
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Database:	MedicLatina

Description
Abstract:	Introduction: The purpose of the study was to describe the experience of treating keloid scars with simultaneous triple therapy (resection, cryotherapy, and intralesional triamcinolone acetonide) in patients treated at a tertiary care institution in Cali, Colombia. Methods: We conducted a descriptive, observational, retrospective study including patients diagnosed with keloid scars who received simultaneous triple therapy between 2017 and 2019. Patients who did not attend follow-up were excluded. Results: A total of 27 patients (17 women) were studied. The average age was 30.8 years (standard deviation: 11.7). The median duration of the keloid scar was 18 years. Phototype V was the most affected (33.3%), and the auricle was the main location (88.9%). Trauma was the most common cause of the scars. Previous treatment with intralesional corticosteroid infiltration was received by 33.3% (9 patients). 63% of patients presented with a single lesion. One lesion per patient was followed up for 6 months, with 66.7% (18 patients) showing no recurrence after treatment. Pain was the most significant adverse effect reported. Conclusions: Simultaneous triple therapy for keloid scar management in our study resulted in a 66.7% non-recurrence rate with minimal complications. This is the first study in Colombia on this treatment for keloid scars. [ABSTRACT FROM AUTHOR]
ISSN:	16570448
DOI:	10.29176/2590843X.1876