View in EDS PDF Full Text

Prevalencia de bronquiectasias en pacientes con errores innatos de la inmunidad.

Saved in:
Bibliographic Details
Title: Prevalencia de bronquiectasias en pacientes con errores innatos de la inmunidad.
Alternate Title: Prevalence of bronchiectasis in patients with inborn errors of immunity.
Authors: Korkowski-Uviña, Karla1 drakarla_korkowski@hotmail.com, Gómez-Hernández, Noemí1, Quintero-Ramos, Antonio2, Contreras-Rodríguez, Felipe de J.3, Ortega-Cisneros, Margarita4
Source: Revista Alergia de Mexico. oct-dic2024, Vol. 71 Issue 4, p229-233. 5p.
Subjects: BRONCHIECTASIS, IMMUNOGLOBULIN G, NATURAL immunity, LUNG infections, RANK correlation (Statistics)
Abstract (English): Objective: To establish the prevalence of bronchiectasis, correlate the IgG IV or SC immunoglobulin dose and serum IgG levels with the total Bhalla score and the severity of bronchiectasis and associate serum IgG levels with the development of pulmonary infectious processes in patients with diagnosis of innate errors of immunity. Methods: A descriptive, observational, cross-sectional study with patients over 18 years of age diagnosed with IBD. Clinical records and computed axial tomography were reviewed. Results: 38 patients with IBD were included, where the prevalence of bronchiectasis was 36.8%. (Regarding the correlation of pulmonary infectious processes with serum IgG levels, a difference was found in patients from 2020 to 2022 (p= 0.002, 0.054, 0.030 respectively). The correlation of severity of bronchiectasis, total score of Bhalla scale, IgG IV or SC immunoglobulin dose and serum IgG levels by Spearman's Rho test I were found to be significantly correlated. Conclusion: It is important to perform chest tomography studies every 3-4 years in patients with IBD to detect timely bronchiectasis, initiate treatment in time, improving patients' quality of life and survival rates, and reducing hospital costs. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Objetivos: Establecer la prevalencia de bronquiectasias, correlacionar la dosis de inmunoglobulina IgG por vía intravenosa o subcutánea y estimar las concentraciones de IgG sérica con el puntaje total de la escala de Bhalla y la gravedad de las bronquiectasias, además de asociar los valores de IgG sérica con los procesos infecciosos pulmonares en pacientes con diagnóstico de errores innatos de la inmunidad. Métodos: Estudio descriptivo, observacional y transversal, llevado a cabo en pacientes mayores de 18 años con diagnóstico de errores innatos de la inmunidad. Se revisaron los expedientes clínicos y las tomografías computadas de cada caso. Resultados: Se registraron 38 pacientes con diagnóstico de errores innatos de la inmunidad. La prevalencia de bronquiectasia fue del 36.8%. Respecto a la correlación de los procesos infecciosos pulmonares con concentraciones de IgG sérica, se encontró diferencia en los pacientes entre los años 2020 y 2022 (p = 0.002, 0.054 y 0.030, respectivamente). Al efectuar la correlación de severidad de bronquiectasias, el puntaje total de escala de Bhalla, las dosis de inmunoglobulina IgG (intravenosa o subcutánea) y las concentraciones séricas de IgG, mediante la prueba Rho de Spearman, se encontró significación estadística. Conclusión: Es importante solicitar estudios de tomografía de tórax cada 3 a 4 años en pacientes con errores innatos de la inmunidad para detectar oportunamente bronquiectasias, instaurar un tratamiento temprano y mejorar la calidad de vida y las tasas de supervivencia de los pacientes, y con ello disminuir los costos hospitalarios. [ABSTRACT FROM AUTHOR]
Copyright of Revista Alergia de Mexico is the property of Coleg. Mexicano de Inmunologia Clinica y Alergia A.C.; Soc. Lat. de Alergia, Asma e Inmunologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
Description
Abstract:Objective: To establish the prevalence of bronchiectasis, correlate the IgG IV or SC immunoglobulin dose and serum IgG levels with the total Bhalla score and the severity of bronchiectasis and associate serum IgG levels with the development of pulmonary infectious processes in patients with diagnosis of innate errors of immunity. Methods: A descriptive, observational, cross-sectional study with patients over 18 years of age diagnosed with IBD. Clinical records and computed axial tomography were reviewed. Results: 38 patients with IBD were included, where the prevalence of bronchiectasis was 36.8%. (Regarding the correlation of pulmonary infectious processes with serum IgG levels, a difference was found in patients from 2020 to 2022 (p= 0.002, 0.054, 0.030 respectively). The correlation of severity of bronchiectasis, total score of Bhalla scale, IgG IV or SC immunoglobulin dose and serum IgG levels by Spearman's Rho test I were found to be significantly correlated. Conclusion: It is important to perform chest tomography studies every 3-4 years in patients with IBD to detect timely bronchiectasis, initiate treatment in time, improving patients' quality of life and survival rates, and reducing hospital costs. [ABSTRACT FROM AUTHOR]
ISSN:00025151
DOI:10.29262/ram.v71i4.1306